RT Journal Article
T1 Binge drinking during adolescence and young adulthood is associated with deficits in verbal episodic memory
A1 Carbia, Carina
A1 Cadaveira Mahía, Fernando
A1 Caamaño Isorna, Francisco
A1 Rodríguez Holguín, Socorro
A1 Corral Varela, María Montserrat
K1 Binge drinking
K1 Adolescence
K1 Verbal memory
K1 Episodic memory
K1 Follow-up study
AB Binge drinking (BD), a harmful pattern of alcohol consumption, is common during adolescence. Young adults with alcohol use disorders exhibit hippocampal alterations and episodic memory deficits. However, it is not known how these difficulties progress in community BD adolescents. Our objective was to analyze the relationship between BD trajectory and verbal episodic memory during the developmental period spanning from adolescence and to early adulthood. An initial sample of 155 male and female first-year university students with no other risk factors were followed over six years. Participants were classified as stable non-BDs, stable BDs and ex-BDs according to the third AUDIT item. At baseline, participants comprised 36 ♂/ 40 ♀ non-BDs (18.58 years), 40 ♂/ 39 ♀ BDs (18.87 years), and at the third follow-up, they comprised 8 ♂/ 8 ♀ stable non-BDs (25.49 years), 2 ♂/ 2 ♀ stable BDs (25.40) and 8 ♂/ 12 ♀ ex-BDs (24.97 years). Episodic memory was assessed four times with the Logical Memory subtest (WMS-III) and the Rey Auditory Verbal Learning Test (RAVLT). Generalized linear mixed models were applied. The results showed that, relative to non-BDs, stable BDs presented difficulties in immediate and delayed recall in the Logical Memory subtest. These difficulties remained stable over time. The short-term ex-BDs continued to display difficulties in immediate and delayed recall in the Logical Memory subtest, but long-term ex-BDs did not. The effects were not influenced by age of alcohol onset, frequency of cannabis use, tobacco use or psychopathological distress. In conclusion, BD during adolescence and young adulthood is associated with episodic memory deficits. Abandoning the BD pattern may lead to partial recovery. These findings are consistent with the vulnerability of the adolescent hippocampus to the neurotoxic effects of alcohol
PB Public Library of Science
YR 2017
FD 2017
LK http://hdl.handle.net/10347/16795
UL http://hdl.handle.net/10347/16795
LA eng
NO Carbia C, Cadaveira F, Caamaño-Isorna F, Rodríguez-Holguín S, Corral M (2017) Binge drinking during adolescence and young adulthood is associated with deficits in verbal episodic memory. PLoS ONE 12(2): e0171393. doi:10.1371/journal.pone.0171393
NO The study was supported by grants from the Spanish Ministerio de Ciencia e Innovación (EDU2008-03400; PSI2011-22575). Carina Carbia was supported by the FPU program (FPU13/04569) of the Spanish Ministerio de Educación
DS Minerva
RD 24 abr 2026