RT Journal Article
T1 CA15.3 Serum Concentrations in Older Women with Infiltrating Ductal Carcinomas of the Breast
A1 Ruibal Morell, Álvaro
A1 Aguiar Fernández, Pablo
A1 Río, María Carmen del
A1 Padín Iruegas, María Elena
A1 Arias, José Ignacio
A1 Herranz Carnero, Michel
K1 Breast cancer
K1 Ductal carcinoma
K1 CA15.3
K1 Elderly
AB Breast cancer is currently becoming a disease of the elderly. We have studied the relation between CA 15.3 serum concentrations and clinical-pathological parameters in 69 women with IDC aged over 70 years (76.3 ± 4.2; range: 71–88; median 76). A group of 205 women with the same tumor but aged <70 years (62.8 ± 4.0; range: 55–70; median 63) was also considered for comparison. Tumor size, axillary lymph node involvement, distant metastasis and histological grade were taken account. Serum CA 15.3 was determined by luminescence assay. CA 15.3 serum concentrations ranged between 6 and 85 U/mL (median 22.9 U/mL), and were higher only in patients with greater (qualitative and quantitative; p: 0.041) tumor size. Our results show that in women with IDCs, and aged over 70 years, serum CA 15.3 serum concentrations are associated exclusively with a greater tumor size, being these findings different to those described in women with the same subtype of tumor considered as a whole or with lower age.
PB MDPI
YR 2014
FD 2014
LK http://hdl.handle.net/10347/21658
UL http://hdl.handle.net/10347/21658
LA eng
NO Ruibal, Á.; Aguiar, P.; Del Río, M.C.; Padín-Iruegas, M.E.; Arias, J.I.; Herranz, M. CA15.3 Serum Concentrations in Older Women with Infiltrating Ductal Carcinomas of the Breast. Int. J. Mol. Sci. 2014, 15, 19870-19876.
NO This work was supported by grant PI11/01806 from ISCIII (Spain)
DS Minerva
RD 24 abr 2026