RT Journal Article
T1 Solid-Phase Extraction and Large-Volume Sample Stacking-Capillary Electrophoresis for Determination of Tetracycline Residues in Milk
A1 Islas, Gabriela
A1 Rodríguez, José A.
A1 Pérez Silva, Irma
A1 Miranda López, José Manuel
A1 Ibarra, Israel S.
AB Solid-phase extraction in combination with large-volume sample stacking-capillary electrophoresis (SPE-LVSS-CE) was applied to measure chlortetracycline, doxycycline, oxytetracycline, and tetracycline in milk samples. Under optimal conditions, the proposed method had a linear range of 29 to 200 µg·L−1, with limits of detection ranging from 18.6 to 23.8 µg·L−1 with inter- and intraday repeatabilities < 10% (as a relative standard deviation) in all cases. The enrichment factors obtained were from 50.33 to 70.85 for all the TCs compared with a conventional capillary zone electrophoresis (CZE). This method is adequate to analyze tetracyclines below the most restrictive established maximum residue limits. The proposed method was employed in the analysis of 15 milk samples from different brands. Two of the tested samples were positive for the presence of oxytetracycline with concentrations of 95 and 126 µg·L−1. SPE-LVSS-CE is a robust, easy, and efficient strategy for online preconcentration of tetracycline residues in complex matrices
PB Hindawi
SN 2090-8865
YR 2018
FD 2018
LK http://hdl.handle.net/10347/19955
UL http://hdl.handle.net/10347/19955
LA eng
NO Gabriela Islas, Jose A. Rodriguez, Irma Perez-Silva, Jose M. Miranda, and Israel S. Ibarra, “Solid-Phase Extraction and Large-Volume Sample Stacking-Capillary Electrophoresis for Determination of Tetracycline Residues in Milk,” Journal of Analytical Methods in Chemistry, vol. 2018, Article ID 5394527, 7 pages, 2018. https://doi.org/10.1155/2018/5394527.
NO The authors wish to thank Programa para el Desarrollo Profesional Docente, para el Tipo Superior (PRODEP) for the approved project in the incorporation of new PTC-Profesores de Tiempo Completo; Consejo Nacional de Ciencia y Tecnología (CONACyT) (Project INFR-2014-227999 and Retention Grant no. 251112) and Xunta de Galicia and Fondo Europeo de Desarrollo Regional (FEDER) (Project GRC 2014/004), for financial support
DS Minerva
RD 28 abr 2026