RT Journal Article
T1 Enzymatic cometabolic biotransformation of organic micropollutants in wastewater treatment plants: a review
A1 Kennes Veiga, David Manuel
A1 González Gil, Lorena
A1 Carballa Arcos, Marta
A1 Lema Rodicio, Juan Manuel
K1 Cometabolism
K1 Enzymes
K1 Omics
K1 Pharmaceuticals
K1 Transformation products
AB Biotransformation of trace-level organic micropollutants (OMPs) by complex microbial communities in wastewater treatment facilities is a key process for their detoxification and environmental impact reduction. Therefore, understanding the metabolic activities and mechanisms that contribute to their biotransformation is essential when developing approaches aiming to minimize their discharge. This review addresses the relevance of cometabolic processes and discusses the main enzymatic activities currently known to take part in OMPs removal under different redox environments in the compartments of wastewater treatment plants. Furthermore, the most common methodologies to decipher such enzymes are discussed, including the use of in vitro enzyme assays, enzymatic inhibitors, the analysis of transformation products and the application of several -omic techniques. Finally, perspectives on major challenges and future research requirements to improve OMPs biotransformation are proposed
PB Elsevier
YR 2022
FD 2022
LK http://hdl.handle.net/10347/27644
UL http://hdl.handle.net/10347/27644
LA eng
NO Bioresource Technology 344 (2022) 126291. https://doi.org/10.1016/j.biortech.2021.126291
NO This research was funded by the Spanish Government (Agencia Estatal de Investigación) through the ANTARES project (PID2019-110346RB-C21) and a PhD Xunta de Galicia Grant (ED481A-2018/113, David Kennes). Authors from Universidade de Santiago de Compostela belong to Galician Competitive Research Group (GRC ED431C 2017/29), which is co-funded by FEDER (EU)
DS Minerva
RD 24 abr 2026