RT Journal Article T1 Quantification of temporomandibular joint space in patients with juvenile idiopathic arthritis assessed by cone beam computerized tomography A1 Otero, María Florinda A1 Tahoces, Pablo G. A1 Mera, Antonio A1 Dalstra, Michel A1 Verna, Carlalberta A1 Pedersen, Thomas Klit A1 Herlin, Troels A1 Mira Pérez, Jorge K1 Cone-beam computed tomography K1 Imaging K1 Inflammation K1 Juvenile idiopathic arthritis K1 TMJ AB ObjectiveTo describe a method to calculate the total intra-articular volume (inter-osseous space) of the temporomandibular joint (TMJ) determined by cone-beam computed tomography (CBCT). This could be used as a marker of tissue proliferation and different degrees of soft tissue hyperplasia in juvenile idiopathic arthritis (JIA) patients.Materials and MethodsAxial single-slice CBCT images of cross-sections of the TMJs of 11 JIA patients and 11 controls were employed. From the top of the glenoid fossa, in the caudal direction, an average of 26 slices were defined in each joint (N = 44). The interosseous space was manually delimited from each slice by using dedicated software that includes a graphic interface. TMJ volumes were calculated by adding the areas measured in each slice. Two volumes were defined: Ve−i and Vi, where Ve−i is the inter-osseous space, volume defined by the borders of the fossa and Vi is the internal volume defined by the condyle. An intra-articular volume filling index (IF) was defined as Ve−i/Vi, which represents the filling of the space.ResultsThe measured space of the intra-articular volume, corresponding to the intra-articular soft tissue and synovial fluid, was more than twice as large in the JIA group as in the control group.ConclusionThe presented method, based on CBCT, is feasible for assessing inter-osseus joint volume of the TMJ and delimits a threshold of intra-articular changes related to intra-articular soft tissue proliferation, based on differences in volumes. Intra-articular soft tissue is found to be enlarged in JIA patients PB Wiley SN 1601-6335 YR 2023 FD 2023-08-01 LK http://hdl.handle.net/10347/31264 UL http://hdl.handle.net/10347/31264 LA eng NO Orthod Craniofac Res. 2023;00:1-8 DS Minerva RD 28 abr 2026