RT Journal Article
T1 Nonleaching Biocidal N-Halamine-Functionalized Polyamine-, Guanidine-, and Hydantoin-Based Coatings
A1 Bromberg, Lev
A1 Magariños Ferro, Beatriz
A1 Concheiro Nine, Ángel Joaquín
A1 Hatton, T. Alan
A1 Álvarez Lorenzo, Carmen
K1 Coating materials
K1 Group 17 compounds
K1 Halogenation
K1 Plants
K1 Polymers
AB Fibrous materials with inherent antimicrobial properties can help in real-time deactivation of microorganisms, enabling multiple uses while reducing secondary infections. Coatings with antiviral polymers enhance the surface functionality for existing and potential future pandemics. Herein, we demonstrated a straightforward route toward biocidal surface creation using polymers with nucleophilic biguanide, guanidine, and hydantoin groups that are covalently attached onto a solid support. Biocidal poly(N-vinylguanidine) (PVG) and poly(allylamine-co-4-aminopyridine-co-5-(4-hydroxybenzylidene)hydantoin) (PAH) were introduced for coating applications along with commercially available polyvinylamine (PVAm) and poly(hexamethylene biguanide) (PHMB). Nonleaching coatings were created by first fabricating bifunctional siloxane or isocyanate precursor coatings on the cotton, nylon–cotton, and glass fiber fabric, followed by the polymer attachment. The developed grafting methods ensured the stability of the coating and the reuse of the material while maintaining the biocidal properties. Halogenation of polymer-coated fabric was conducted by aqueous solutions of sodium hypochlorite or in situ generation of hypobromous acid (HOBr), resulting in surfaces coated by N-halamines with high contents of active > N–Cl or > N–Br groups. The polymer-coated fabrics were stable in multiple laundry cycles and maintained hydrophilic character after coating and halogenation. Halogenated polymer-coated fabrics completely inactivated human respiratory coronavirus based on a contact-killing mechanism and were shown to be reusable after recharging with bromine or chlorine
PB American Chemical Society
SN 0888-5885
YR 2024
FD 2024
LK http://hdl.handle.net/10347/33865
UL http://hdl.handle.net/10347/33865
LA eng
NO Lev Bromberg, Beatriz Magariños, Angel Concheiro, T. Alan Hatton, and Carmen Alvarez-Lorenzo Industrial & Engineering Chemistry Research 2024 63 (14), 6268-6278 DOI: 10.1021/acs.iecr.4c00320
NO The work was supported by MCIN/AEI/10.13039/501100011033 [PID 2020-113881RB-I00], Spain, Xunta de Galicia [ED431C 2020/17; ED431C 2022/23], and FEDER
DS Minerva
RD 24 abr 2026