RT Journal Article T1 Optimization of the Yacovino maneuver for superior canal BPPV using numerical simulations A1 Arán Tapia, Ismael A1 Bastos Costas, Guillermo A1 Pérez Muñuzuri, Alberto K1 Benign paroxysmal positional vertigo K1 Yacovino maneuver K1 Computational fluid dynamics K1 Mathematical modeling AB We evaluated the effectiveness of the original Yacovino maneuver (YM) for treating superior canal benign paroxysmal positional vertigo (SC-BPPV) using numerical simulations and proposed modifications to enhance its efficacy. A high-resolution three-dimensional micro-computed tomography (μCT) reconstruction of a human membranous labyrinth was used to simulate the BPPV condition. Endolymphatic fluid dynamics were modeled by solving the Navier–Stokes equations, and otoconia of varying sizes (3–30 µm) were introduced as Lagrangian particles. Their displacement was tracked using a superior canal-centric polar coordinate system. Two maneuver protocols were simulated: the original YM and a modified version with adjusted rotational angles and a 30-second resting interval per step. The original YM resulted in otoconia trapping in the ampulla and canal switching, limiting its effectiveness. In contrast, the modified YM—in which the patient lies face down with a 50° head flexion in the initial step, followed by optimized subsequent rotations—significantly improved otoconia migration toward the utricular macula. Longer resting times further enhanced the displacement of smaller particles without compromising maneuver safety. These findings suggest that the modified YM is a safe and effective alternative for SC-BPPV treatment. Tailoring rotation angles based on anatomical variability may improve outcomes, though clinical validation is still required. PB Elsevier SN 0378-5955 YR 2025 FD 2025-07-22 LK https://hdl.handle.net/10347/43846 UL https://hdl.handle.net/10347/43846 LA eng NO Arán-Tapia, I., Bastos, G., & P․ Muñuzuri, A. (2025). Optimization of the Yacovino maneuver for superior canal BPPV using numerical simulations. Hearing Research, 466, 109374. 10.1016/j.heares.2025.109374 NO This research is supported by the Spanish Ministerio de Economía y Competitividad and the European Regional Development Fund, through research grant PID2022–138322OB-100, funded by MCIN/AEI/ 10.13039/501100011033 and by “ERDF A Way of Making Europe.” It is also supported by Xunta de Galicia under research grant no. 2021- PG036, and the Instituto de Salud Carlos III (ISCIII) under grant number PI23/00248. DS Minerva RD 24 may 2026