RT Journal Article
T1 Anorexia nervosa and microbiota: systematic review and critical appraisal
A1 García Rodríguez, Naomi
A1 Gutiérrez García, Emilio
K1 Anorexia nervosa
K1 Microbiota
K1 Gut-brain axis
K1 Dysbiosis
AB Purpose: Recent studies have reported a gut microbiota imbalance or dysbiosis associated with anorexia nervosa (AN), which has prompted an appraisal of its aetiological role, and the reformulation of AN as a metabo-psychiatric disorder. Thus, the aim of this paper was to critically review the current scientific findings regarding the role of microbiota in anorexia nervosa. Methods: A systematic study of peer-reviewed literature published in four databases between 2009 and 2022 was conducted according to PRISMA guidelines. Both human and animal studies were included.Results: A total of 18 studies were included. In animal models, both the preclinical and clinical findings were inconsistent regarding microbiota composition, faecal metabolite concentrations, and the effects of human faecal microbiota transplants. Conclusion: The methodological limitations, lack of standardisation, and conceptual ambiguity hinder the analysis of microbiota as a key explanatory factor for AN
PB Springer
SN 1124-4909
YR 2023
FD 2023
LK http://hdl.handle.net/10347/30372
UL http://hdl.handle.net/10347/30372
LA eng
NO Garcia, N., Gutierrez, E. Anorexia nervosa and microbiota: systematic review and critical appraisal. Eat Weight Disord 28, 1 (2023). https://doi.org/10.1007/s40519-023-01529-4
NO Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature
DS Minerva
RD 28 abr 2026