RT Journal Article
T1 Synthesis and X-ray Diffraction Study of thiosemicarbazone Palladacycles with dppm
A1 Rúa Sueiro, Marcos
A1 Munín Cruz, Paula
A1 Reigosa Chamorro, Francisco
A1 Vila Abad, José Manuel
A1 Ortigueira Amor, Juan Manuel
K1 Cyclometallation
K1 Thiosemicarbazone
K1 Palladium
K1 Platinum
K1 X-ray diffraction
AB Cyclometallated compounds have been extensively studied, in particular those with palladium and platinum. This is because of their possible applications in medicinal chemistry, as anticancer or antimicrobial agents; in some cases, with similar results as cisplatin, carboplatin or oxaliplatin. What is also remarkable is their use as homogeneous catalysts, for example, in cross coupling reactions such as Suzuki–Miyaura or Mizoroki–Heck. Herein, we report the synthesis of different thiosemicarbazone ligands, which will be reacted with a palladium or platinum salt, to give the corresponding cyclometallated compounds; in addition, their reactivity with bis(diphenylphosphino)methane (dppm) will be studied. Characterization has been carried out by elemental analysis, IR spectroscopy, 1H and 31P NMR spectroscopy. Additionally, 1c has been studied by X-ray diffraction
PB MDPI
YR 2021
FD 2021
LK http://hdl.handle.net/10347/24466
UL http://hdl.handle.net/10347/24466
LA eng
NO Proceedings 2020, 62(1), 13; https://doi.org/10.3390/proceedings2020062013
NO Francisco Reigosa wants to thank the Spanish Government (AEI) for their financial support through an FPU grant (number 13/05014). The authors thank funding from Xunta de Galicia (Galicia, Spain) under the Grupos de Referencia program (GRC 2019/014)
DS Minerva
RD 28 abr 2026