RT Journal Article
T1 NIR-Emitting Alloyed CdTeSe QDs and Organic Dye Assemblies: A Nontoxic, Stable, and Efficient FRET System
A1 Ramírez Herrera, Doris E.
A1 Rodríguez Velázquez, Eustolia
A1 Alatorre Meda, Manuel
A1 Paraguay Delgado, Francisco
A1 Tirado Guízar, Antonio
A1 Taboada Antelo, Pablo
A1 Pina Luis, Georgina
K1 Energy transfer
K1 Alloyed quantum dots
K1 Quantum dots-dye assemblies
K1 Cytocompatibility
AB In the present work, we synthesize Near Infrared (NIR)-emitting alloyed mercaptopropionicacid (MPA)-capped CdTeSe quantum dots (QDs) in a single-step one-hour process, without theuse of an inert atmosphere or any pyrophoric ligands. The quantum dots are water soluble,non-toxic, and highly photostable and have high quantum yields (QYs) up to 84%. The alloyedMPA-capped CdTeSe QDs exhibit a red-shifted emission, whose color can be tuned between visibleand NIR regions (608–750 nm) by controlling the Te:Se molar ratio in the precursor mixtures and/orchanging the time reaction. The MPA-capped QDs were characterized by UV-visible absorptionspectroscopy, fluorescence spectroscopy, transmission electron microscopy (TEM), energy dispersiveX-ray spectroscopy (EDS), and zeta potential measurements. Photostability studies were performedby irradiating the QDs with a high-power xenon lamp. The ternary MPA-CdTeSe QDs showed greaterphotostability than the corresponding binary MPA-CdTe QDs. We report the Förster resonance energytransfer (FRET) from the MPA-capped CdTeSe QDs as energy donors and Cyanine5 NHS-ester (Cy5)dye as an energy acceptor with efficiency (E) up to 95%. The distance between the QDs and dye (r),the Förster distance (R0), and the binding constant (K) are reported. Additionally, cytocompatibilityand cell internalization experiments conducted on human cancer cells (HeLa) cells revealed thatalloyed MPA-capped CdTeSe QDs are more cytocompatible than MPA-capped CdTe QDs and arecapable of ordering homogeneously all over the cytoplasm, which allows their use as potential safe,green donors for biological FRET applications.
PB MDPI
YR 2018
FD 2018
LK http://hdl.handle.net/10347/22805
UL http://hdl.handle.net/10347/22805
LA eng
NO Ramírez-Herrera, D. E., Rodríguez-Velázquez, E., Alatorre-Meda, M., Paraguay-Delgado, F., Tirado-Guízar, A., Taboada, P., & Pina-Luis, G. (2018). NIR-Emitting Alloyed CdTeSe QDs and Organic Dye Assemblies: A Nontoxic, Stable, and Efficient FRET System. Nanomaterials (Basel, Switzerland), 8(4), 231. https://doi.org/10.3390/nano8040231
NO G.P.-L. gratefully acknowledge support from Consejo Nacional de Ciencia y Tecnología(CONACyT), México (Project 167139), Tecnológico Nacional de México (TecNM) (Project 6281.17-P),and Supramolecular Chemistry Network (CONACyT, Project 271884). E.R.-V. thanks PRODEP (UABC) throughProject NPTC 2017-305/488/E. M.A.-M. thanks funding from CONACyT (Mexico) through Research ProjectsINFR-2015-251863 and PDCPN-2015-89. P.T. thanks AEI and FEDER for research project MAT2016-80266-R andadditional funding. D. Ramírez-Herrera thanks CONACyT for a doctoral fellowship
DS Minerva
RD 24 abr 2026