RT Journal Article
T1 Categorization of the Aqueous Deficient Dry Eye by a Cut-Off Criterion of TMH Measured with Tearscope
A1 Sabucedo Villamarín, Belén
A1 Pena Verdeal, Hugo
A1 Yebra-Pimentel Vilar, Eva
A1 García Queiruga, Jacobo
A1 Giráldez Fernández, María Jesús
A1 García Resúa, Carlos
K1 ADDE
K1 TMH
K1 Tear Film and Ocular Surface Society in the second Dry Eye Workshop (TFOS DEWS-II)
K1 Tearscope
K1 Cut-off value
AB A decrease in the Tear Meniscus Height (TMH) has been proposed as a useful indicator for Aqueous Deficient Dry Eye (ADDE) categorization. The present study aimed to calculate a TMH cut-off criterion for the ADDE categorisation or severity assessment with the Tearscope. 200 participants with a previous Dry Eye Disease (DED) diagnosis according to TFOS DEWS-II criteria were recruited. TMH by slit-lamp illumination and Lipid Layer Pattern (LLP) with Tearscope were assessed to categorise the participants into the ADDE or the Evaporative Dry Eye (EDE) group. The ADDE group was also subdivided into Mild-moderate ADDE and Moderate-severe ADDE based on TMH with slit-lamp. Additionally, the TMH was measured by Tearscope (TMH-Tc). Receiver Operating Characteristics showed that the TMH-Tc have a diagnostic capability to differentiate between ADDE and EDE participants, and between Mild-moderate or Moderate-severe ADDE, with a cut-off value of 0.159 mm (AUC = 0.843 ± 0.035, p < 0.001; sensitivity: 86.4%; specificity: 75.4%) and 0.105 mm (AUC = 0.953 ± 0.025, p < 0.001; sensitivity: 98.1%; specificity: 80.0%), respectively. The present study proposed a cut-off criterion to differentiate between ADDE and EDE participants, or between ADDE severities through TMH assessed by Tearscope.
PB MDPI
SN 2075-1729
YR 2022
FD 2022-12
LK http://hdl.handle.net/10347/32058
UL http://hdl.handle.net/10347/32058
LA eng
DS Minerva
RD 24 abr 2026