RT Journal Article T1 Towards improved magnetic fluid hyperthermia: major-loops to diminish variations in local heating A1 Muñoz Menéndez, Cristina A1 Serantes Abalo, David A1 Ruso Beiras, Juan Manuel A1 Baldomir Fernández, Daniel K1 Magnetic hyperthermia K1 Magnetic nanoparticles K1 Local heating AB In the context of using magnetic nanoparticles for heat-mediated applications, the need of an accurate knowledge of the local (at the nanoparticle level) heat generation in addition to the usually studied global counterpart has been recently highlighted. Such a need requires accurate knowledge of the links among the intrinsic particle properties, system characteristics and experimental conditions. In this work we have investigated the role of the particles' anisotropy polydispersity in relation to the amplitude (Hmax) of the AC magnetic field using a Monte Carlo technique. Our results indicate that it is better to use particles with large anisotropy for enhancing global heating, whereas for achieving homogeneous local heating it is better to use lower anisotropy particles. The latter ensures that most of the system undergoes major-loop hysteresis conditions, which is the key-point. This is equivalent to say that low-anisotropy particles (i.e. with less heating capability) may be better for accurate heat-mediated applications, which goes against some research trends in the literature that seek for large anisotropy (and hence heating) values PB Royal Society of Chemistry SN 1463-9076 YR 2017 FD 2017-05-11 LK http://hdl.handle.net/10347/16803 UL http://hdl.handle.net/10347/16803 LA eng NO Munoz-Menendez, C., Serantes, D., Ruso, J., & Baldomir, D. (2017). Towards improved magnetic fluid hyperthermia: major-loops to diminish variations in local heating. Physical Chemistry Chemical Physics, 19(22), 14527-14532. doi: 10.1039/c7cp01442b NO This is the accepted manuscript of the following citation: Munoz-Menendez, C., Serantes, D., Ruso, J., & Baldomir, D. (2017). Towards improved magnetic fluid hyperthermia: major-loops to diminish variations in local heating. Physical Chemistry Chemical Physics, 19(22), 14527-14532. doi: 10.1039/c7cp01442b NO The authors thank the Centro de Supercomputacio ´n de Galicia (CESGA) for the computational facilities. This work was co-financed by the Spanish MINECO (Project MAT2013-47078-C22-P), Xunta de Galicia, Spain (Project GRC 2014/013, ‘Programa de axudas a ´ etapa predoutoral’ and financial support of D.S. under Plan I2C) and ‘Fondo Social Europeo 2014/2020’ DS Minerva RD 29 abr 2026