RT Journal Article T1 Effects of calving body condition score on blood acid–base balance of primiparous Holstein-Friesian dairy cows in a commercial dairy farm: a case study A1 Muiño Otero, Rodrigo A1 Hernández Bermúdez, Joaquín A1 Benedito Castellote, José Luis A1 Castillo Rodríguez, Cristina K1 Heifers K1 Parturition K1 Body condition score K1 Nutrition K1 Acid–base balance K1 Milk yield AB The study was carried out on 27 healthy primiparous Holstein heifers (620 ± 50 kg) kept in a commercial dairy herd. The animals were divided into two groups taking into account the body condition score (BCS) index: BCS < 3.5, n = 12; BCS > 3.5 n = 15. The study period started one month before calving (BC), and ran until one month after calving (AC). Venous blood samples were collected 1 month and 1 week BC, and 1 week and 1 month AC. This study had two objectives: (i) to assess whether a higher or lower BCS affected total milk production and its quality; (ii) to assess changes in the internal fluid (venous pH; partial pressure of CO2, ppCO2; bicarbonate; total CO2, TCO2; base excess, BE; electrolytes Na+, K+, Cl−; and anion gap, AG) that occur during this phase depending on the BCS. We can conclude that the BCS at calving does not affect the productive status during lactation, both in terms of the quantity and quality of milk produced. The excess of crude protein (CP) added through the ration in the lactation phase can trigger a tendency to an alkalotic state, in this case compensated by respiratory buffering mechanisms, as reflected by the TCO2. The changes in electrolytes are a reflection of the movement of free water for milk production, where a balance between measurable anions and cations is observed PB MDPI YR 2021 FD 2021 LK http://hdl.handle.net/10347/26648 UL http://hdl.handle.net/10347/26648 LA eng NO Muiño Otero, R., Hernández Bermúdez, J., Benedito Castellote, J. L. & Castillo Rodríguez, C. (2021). Effects of calving body condition score on blood acid–base balance of primiparous Holstein-Friesian dairy cows in a commercial dairy farm: a case study. Animals, 11(7), 2075-. https://doi.org/10.3390/ani11072075 NO This study was financed in part by Proxectos Plan Galego IDT (Code 2017-PG138) de la Consellería de Medio Rural de la Xunta de Galicia (Proyects Galician IDT Plan of the Ministry of Rural Environment of Xunta de Galicia) (FEADER 2017/057B). The title of the project was: “Sistema de control y valoración de la eficiencia de las explotaciones ganaderas para la producción sostenible de leche” (System of control and evaluation of the efficiency of livestock farms for the sustainable production of milk) DS Minerva RD 28 abr 2026