RT Journal Article
T1 Functional activation and connectivity of the left inferior frontal gyrus during lexical and phonological retrieval
A1 Rivas Fernández, Miguel Ángel
A1 Varela-López, Benxamín
A1 Cid Fernández, Susana
A1 Galdo Álvarez, Santiago
K1 Naming
K1 fMRI
K1 Task functional connectivity
K1 Left inferior frontal gyrus
AB Being language a paradigm of structural and functional asymmetry in cognitive processing, the left Inferior Frontal Gyrus has been consistently related to speech production. In fact, it has been considered a key node in cortical networks responsible for different components of naming. However, isolating these components (e.g., lexical, syntactic, and phonological retrieval) in neuroimaging studies is difficult due to the use of different baselines and tasks. In the present study, functional activation and connectivity of the left inferior frontal gyrus was explored using functional magnetic resonance imaging. Participants performed a covert naming task (pressing a button based on a phonological characteristic). Two conditions were compared: drawings of objects and single letters (baseline condition). Differences in activation and functional connectivity were obtained for objects and letters in different areas of the left Inferior Frontal Gyrus. The pars triangularis was involved in the retrieval of lexical-phonological information, showing a pattern of connectivity with temporal areas in the search for the name of objects and with perisylvanian areas for letters. Selection of phonological information seems to involve the pars opercularis both to letters and objects but recruiting supramarginal and superior temporal areas to letters, probably related to  orthographicphonological conversion. The results support the notion of the left Inferior Frontal Gyrus as a buffer forwarding neural information across cortical networks responsible for different components of speech production.
PB MDPI
SN 2073-8994
YR 2021
FD 2021
LK http://hdl.handle.net/10347/27502
UL http://hdl.handle.net/10347/27502
LA eng
NO Rivas-Fernández, M.Á.; Varela-López, B.; Cid-Fernández, S.; Galdo-Álvarez, S. Functional Activation and Connectivity of the Left Inferior Frontal Gyrus during Lexical and Phonological Retrieval. Symmetry 2021, 13, 1655
NO This research was funded by the Spanish Ministerio de Economía y Competitividad (Grant number: PSI2013 43594-R), Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia (Grant number: ED431C-2021/04, from the EDRF/FEDER) and by a post-doctoral fellowship from Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia (Grant number: ED481B2016/078-0). The funding sources were not involved in any aspect of the research or the submission of this study
DS Minerva
RD 29 abr 2026