RT Dissertation/Thesis
T1 Rh(III)-catalyzed annulations based on C-H activation. Sustainable synthesis of carbo- and heterocycles
A1 Seoane Fernández, Andrés
K1 Organometallic chemistry
K1 catalysis
K1 C-H activation
K1 annulations
AB One of the main challenges still present within organic synthesis is the ability to achievecomplex molecules with high efficiency. In this context metal-catalyzed C-H functionalizationprocesses have gained a lot of attraction due to their ability to increase molecular complexityin few steps and with a minimum generation of waste. These kind of reactions occurs througha metallacyclic intermediate which can be trapped with a huge variety of unsaturated productsby a cycloaddition step. This combination of C-H activation and cycloaddition allows to obtaincyclic structures in few steps and high yields. The work realized within my PhD periodembraces the field of C-H activation through the development of novel reactivity patterns inRhodium (III)-catalyzed oxidative annulation reactions. These processes allow to obtaininterseting biological and/or biomedic compounds with a high atom and step economy fromsimple comercial precursors.
YR 2016
FD 2016
LK http://hdl.handle.net/10347/14933
UL http://hdl.handle.net/10347/14933
LA eng
DS Minerva
RD 29 abr 2026