RT Journal Article
T1 Melatonin: a review of its potential functions and effects on dental diseases
A1 Permuy Mendaña, María
A1 López Peña, Mónica
A1 González Cantalapiedra, Antonio
A1 Muñoz Guzón, Fernando María
K1 Melatonin
K1 Oral cavity
K1 Implants
K1 Periodontal disease
AB Melatonin is a hormone synthesised and secreted by the pineal gland and other organs. Its secretion, controlled by an endogenous circadian cycle, has been proven to exert immunological, anti-oxidant, and anti-inflammatory effects that can be beneficial in the treatment of certain dental diseases. This article is aimed at carrying out a review of the literature published about the use of melatonin in the dental field and summarising its potential effects. In this review article, an extensive search in different databases of scientific journals was performed with the objective of summarising all of the information published on melatonin use in dental diseases, focussing on periodontal diseases and dental implantology. Melatonin released in a natural way into the saliva, or added as an external treatment, may have important implications for dental disorders, such as periodontal disease, as well as in the osseointegration of dental implants, due to its anti-inflammatory and osseoconductive effects. Melatonin has demonstrated to have beneficial effects on dental pathologies, although further research is needed to understand the exact mechanisms of this molecule
PB MDPI
SN 1422-0067
YR 2017
FD 2017-04
LK http://hdl.handle.net/10347/15933
UL http://hdl.handle.net/10347/15933
LA eng
NO Permuy, M., López-Peña, M., González-Cantalapiedra, A., & Muñoz, F. (2017). Melatonin: A Review of Its Potential Functions and Effects on Dental Diseases. International journal of molecular sciences, 18(4), 865.
DS Minerva
RD 28 abr 2026