RT Journal Article
T1 Estimates of recent and historical effective population size in turbot, seabream, seabass and carp selective breeding programmes
A1 Saura, María
A1 Caballero, Armando
A1 Santiago, Enrique
A1 Fernández, Almudena
A1 Morales-Gonzalez, Elisabeth
A1 Fernández, Jesús
A1 Cabaleiro, Santiago
A1 Millán, Adrián
A1 Martínez Portela, Paulino
A1 Palaiokostas, Christos
A1 Kocour, Martin
A1 Aslam, Muhammad L
A1 Houston, Ross D.
A1 Prchal, Martin
A1 BARGELLONI, Luca
A1 Tzokas, Kostas
A1 Haffray, Pierrick Yann Tudy
A1 Bruant, Jean-Sebastien
A1 Villanueva, Beatriz
K1 Cyprinus carpio
K1 Cyprinus carpi
K1 Dicentrarchus labrax
K1 Scophthalmus maximus
K1 Scophthalmidae
AB BackgroundThe high fecundity of fish species allows intense selection to be practised and therefore leads to fast genetic gains. Based on this, numerous selective breeding programmes have been started in Europe in the last decades, but in general, little is known about how the base populations of breeders have been built. Such knowledge is important because base populations can be created from very few individuals, which can lead to small effective population sizes and associated reductions in genetic variability. In this study, we used genomic information that was recently made available for turbot (Scophthalmus maximus), gilthead seabream (Sparus aurata), European seabass (Dicentrarchus labrax) and common carp (Cyprinus carpio) to obtain accurate estimates of the effective size for commercial populations.MethodsRestriction-site associated DNA sequencing data were used to estimate current and historical effective population sizes. We used a novel method that considers the linkage disequilibrium spectrum for the whole range of genetic distances between all pairs of single nucleotide polymorphisms (SNPs), and thus accounts for potential fluctuations in population size over time.ResultsOur results show that the current effective population size for these populations is small (equal to or less than 50 fish), potentially putting the sustainability of the breeding programmes at risk. We have also detected important drops in effective population size about five to nine generations ago, most likely as a result of domestication and the start of selective breeding programmes for these species in Europe.ConclusionsOur findings highlight the need to broaden the genetic composition of the base populations from which selection programmes start, and suggest that measures designed to increase effective population size within all farmed populations analysed here should be implemented in order to manage genetic variability and ensure the sustainability of the breeding programmes
PB Springer
SN 1297-9686
YR 2021
FD 2021
LK http://hdl.handle.net/10347/32002
UL http://hdl.handle.net/10347/32002
LA eng
NO Saura, M., Caballero, A., Santiago, E. et al. Estimates of recent and historical effective population size in turbot, seabream, seabass and carp selective breeding programmes. Genet Sel Evol 53, 85 (2021). https://doi.org/10.1186/s12711-021-00680-9
NO This work was supported by the European Union’s Seventh Framework Programme (KBBE.2013.1.2-659 10 under Grant Agreement No. 613611 FISHBOOST project), the European Commission Horizon 2020 (H2020) Framework Programme through grant agreement no 727315 MedAID project (Mediterranean Aquaculture Integrated Development), by Ministerio de Ciencia e Innovación (CGL2016-75904-C2), MCIN/AEI/https://doi.org/10.13039/501100011033 (PID2020-114426GB-C22 and PID2020-114426GB-C2), Xunta de Galicia (GRC, ED431C 2020-05) and Centro singular de investigación de Galicia accreditation 2019–2022, and the European Union (European Regional Development Fund—ERDF), Fondos Feder “Unha maneira de facer Europa”. MK and MP were also supported by Ministry of Education, Youth and Sports of the Czech Republic—project Biodiverzity (CZ.02.1.01/0.0/0.0/16_025/0007370). The Roslin Institute was partly funded by Biotechnology and Biological Sciences Research Council Institute Strategic Programme grants (BBS/E/D/20241866, BBS/E/D/20002172 and BBS/E/D/20002174)
DS Minerva
RD 27 abr 2026