RT Journal Article
T1 J‐filter: An experiment to simplify and isolate specific signals in 1H NMR spectra of complex mixtures based on scalar coupling constants
A1 Vilela Góñez, Karen
A1 Suárez García, Juan
A1 Sardina López, Francisco Javier
A1 Pazos, Yolanda
A1 Saá, Ángela
A1 Martín Pastor, Manuel
K1 NMR of mixtures
K1 NMR scalar coupling filter
K1 Selective experiment
K1 Signal edition and filtering
AB One-dimensional selective NMR experiments relying on a J-filter element are proposed to isolate specific signals in crowded 1H spectral regions. The J-filter allows the edition or filtering of signals in a region of interest of the spectrum by exploiting the specific values of their 1H-1H coupling constants and certain parameters of protons coupled to them that appear in less congested parts of the spectrum (chemical shifts and coupling constants). The new experiments permitted the isolation of specific peaks of phytosterol components in a sample obtained from a liquid nutraceutical recommended for lowering blood cholesterol levels in regions with complete overlap in the 1H spectrum.
PB Wiley
SN 0749-1581
YR 2023
FD 2023
LK http://hdl.handle.net/10347/32988
UL http://hdl.handle.net/10347/32988
LA eng
NO K. V. Góñez, J. S. García, F. J. Sardina, Y. Pazos, Á. Saá, M. Martín−Pastor, J-filter: An experiment to simplify and isolate specific signals in 1H NMR spectra of complex mixtures based on scalar coupling constants. Magn Reson Chem 2023, 61(11), 615. https://doi.org/10.1002/mrc.5396
NO K.V.G., J.S.G., and F.J.S. thank the Xunta de Galicia (Centro Singular de Investigación de Galicia accreditation 2019–2022, ED431G2019/03), and the European Regional Development Fund (ERDF) is gratefully acknowledged. M.M.-P. and J.S. thank the Galician Innovation Agency (GAIN) for the funding of this project (title BIOTICFINDER, Programa Conecta COVID, 2021-PG082). A.S.H. thanks the SmartGlobalLab project (Nº 2021/C005/00150505) under the 2021 Call for grants for research and development projects in artificial intelligence and other digital technologies and their integration in value chains (C005/21-ED), funded by the European Union–NextGenerationEU.
DS Minerva
RD 4 may 2026