RT Journal Article T1 Validation of Potential Effects on Human Health of in Vivo Experimental Models Studied in Rats Exposed to Sub-Thermal Radiofrequency. Possible Health Risks Due to the Interaction of Electromagnetic Pollution and Environmental Particles A1 Salas Sánchez, Aarón Ángel A1 López Furelos, Alberto A1 Rodríguez González, Juan Antonio A1 Ares Pena, Francisco José A1 López Martín, María Elena K1 Bioelectromagnetic effects K1 Electromagnetic radiation effects K1 Specific absorption rate AB Studies are based on the exposure of Sprague–Dawley rats (250 male and 250 femalerats) to electromagnetic fields (EMF) at different frequencies in standing and travelling wave chambers.Values of specific absortion rate (SAR) for all of these experiments were obtained from commerciallyavailable FDTD-based simulation software based on numerical phantom animals. An experimental radiationsystem was developed with a standing-wave cavity which keeps electromagnetic parameters constant whilefacilitating stress-free exposure of animals to non-thermal radiation. This makes it possible to directlymeasure the power absorbed by the animal and determine whole-body mean SAR according to weight.All studies using this setup were performed with global system for mobile communication (GSM) radiationat 900 MHz. The simple picrotoxin model made allow to identify morphological signs of neurotoxicity inrat brain tissue. Experiments involving travelling waves were done in a commercial Gigahertz TransverseElectroMagnetic (GTEM) chamber connected to one or two vector signal generators (to carry singleor multiple EMF exposure frequencies). In the diathermy model, rat thyroid and thymus exposed to2.45 GHz radiation showed visible morphological and immune effects. Cellular stress in the cerebral cortex,the cerebellum or both seems to be more associated with the type of signal than with additive effects ofcombined frequencies. Finally, some hypothesis related with the future models about the ElectroMagnetic(EM) pollution are established. In an urban environmental that combines the electromagnetic and chemicalpollution of environmental particles, cortical excitability, inflammatory response, and cell injury can bemodified. PB IEEE YR 2019 FD 2019 LK http://hdl.handle.net/10347/21350 UL http://hdl.handle.net/10347/21350 LA eng NO A. A. Salas-Sánchez, A. López-Furelos, J. A. Rodríguez-González, F. J. Ares-Pena and M. E. López-Martín, "Validation of Potential Effects on Human Health of in Vivo Experimental Models Studied in Rats Exposed to Sub-Thermal Radiofrequency. Possible Health Risks Due to the Interaction of Electromagnetic Pollution and Environmental Particles," in IEEE Access, vol. 7, pp. 79186-79198, 2019 NO This work was supported in part by the FEDER/Ministerio de Ciencia, Innovación y Universidades-Agencia Estatal de Investigación underProject TEC2017-86110-R DS Minerva RD 3 may 2026