RT Dissertation/Thesis
T1 Personalised Medicine in Endometrial Cancer Through the Use of Liquid Biopsy
A1 Casas Arozamena, Carlos
K1 liquid biopsy
K1 precision medicine
K1 endometrial cancer
AB Although usually associated with good clinical outcome, endometrial cancer incidence and mortality has been rising over the past years. To tackle the different clinical challenges required to change this negative evolution, in the current doctoral thesis we studied minimally invasive samples such as the uterine aspirate and plasma samples to better understand the molecular characteristics of this tumour and to validate accurate prognostic and follow-up tools and new therapeutic targets. Moreover, we combined these tools with the development of patient derived preclinical models for personalized pharmacological studies. Overall, the results obtained in this thesis demonstrated the value of liquid-biopsybased pipelines to improve the management of localised and advanced endometrial cancer patients.
YR 2024
FD 2024
LK https://hdl.handle.net/10347/37775
UL https://hdl.handle.net/10347/37775
LA eng
DS Minerva
RD 26 abr 2026