RT Journal Article
T1 Clinical performance of an objective methodology to categorize tear film lipid layer patterns
A1 García Resúa, Carlos
A1 Pena Verdeal, Hugo
A1 Giráldez Fernández, María Jesús
A1 Yebra-Pimentel Vilar, Eva
K1 Lipid layer pattern
K1 Tearscope-plus
K1 Tear film
K1 Interference phenomena
AB Purpose: To validate the performance of a new objective application designated iDEAS (Dry Eye Assessment System) to categorize different zones of lipid layer patterns (LLPs) in one image. Material and methods: Using the Tearscopeplus and a digital camera attached to a slit-lamp, 50 images were captured and analyzed by 4 experienced optometrists. In each image, the observers outlined tear film zones identified as a specific LLP. Further, the categorization by the 4 optometrists (observers 1, 2, 3 and 4) was compared with the automatic system included in iDEAS (5th observer). Results: In general, observer 3 was classified as worse than all observers (observers 1, 2, 4 and automatic application, Wilcoxon test, <0.05). The automatic system behaved similarly to the remaining three observers (observers 1, 2 and 4) showing differences only for Open Meshwork LLP when compared with observer 4 (Wilcoxon test, p=0.02). For the remaining two observers (observers 1 and 2) there were not found statistical differences (Wilcoxon test, >0.05). Furthermore, we obtained a set of photographs per LLP category for which all optometrists showed agreement by using the new tool. After examining them, we detected the more characteristic features of each LLP to enhance the description of the patterns implemented by Guillon. Conclusions: The automatic application in the iDEAS framework can provide zones similar to the annotations made by experienced optometrists. Thus, the manual process done by experts can be automated with the benefit of being unaffected by subjective factors.
PB SPIE
SN 0277-786X
YR 2017
FD 2017
LK http://hdl.handle.net/10347/32799
UL http://hdl.handle.net/10347/32799
LA eng
NO García Resúa, C., Pena Verdeal, H., Giráldez, M.J., Yebra-Pimentel Vilar, E. (2017) Clinical performance of an objective methodology to categorize tear film lipid layer patterns, Proceedings of SPIE, vol. 10453
DS Minerva
RD 24 abr 2026