RT Dissertation/Thesis
T1 New molecular mechanisms and novel biomarkers associated with Extracellular Vesicles in Polycystic Kidney Disease: from preclinical models to patients
A1 Vizoso González, Marta
K1 Polycystic Kidney Disease
K1 ADPKD
K1 cystogenesis
K1 therapeutic target
K1 biomarkers
K1 Extracellular Veislces
AB The Polycystic Kidney Disease involves a group of diseases, which arecharacterized by the presence of cyst in nephrons from both kidneys, leading to kidney failure to the majority ofpeople affected. The Polycystic Kidney Disease is a global public health problem, being one of the most commonhereditary syndromes. Despite its importance, there is a lack of early diagnosis and effective therapy, apart fromrenal replacement therapy. Due to this, the principal objectives of this project are focused on the research themolecular mechanism that is involved in the development of the Polycystic Kidney Disease with the aim ofelucidating the key mechanism for cystogenesis that will allow us to find a new effective therapeutic target for thetreatment of polycystic kidney disease; and the development of new diagnostic tools that complement with thegenetic diagnosis our group do and also allow us to anticipate the evolution of the disease.
YR 2023
FD 2023
LK http://hdl.handle.net/10347/30086
UL http://hdl.handle.net/10347/30086
LA eng
DS Minerva
RD 28 abr 2026