RT Book,_Section
T1 Cyclization and self-assembly of cyclic peptides
A1 Méndez Ardoy, Alejandro
A1 Insua López, Ignacio
A1 Granja Guillán, Juan Ramón
A1 Montenegro García, Javier
A2 Coppock, Matthew B.
A2 Winton, Alexander J.
K1 Therapeutics
K1 Discovery and development
K1 Synthetic approaches
K1 Combinatorial libraries
K1 Screening
K1 Cyclic peptides
K1 Solid-phase synthesis
K1 Self-assembly
K1 Supramolecular chemistry
K1 Nanotubes
AB Cyclic peptides are a fascinating class of molecules that can be programmed to fold or self-assemble into diverse mono- and multidimensional structures with potential applications in biomedicine, nanoelectronics, or catalysis. Herein we describe on-resin procedures to carry out head-to-tail peptide cyclization based on orthogonal protected linear structures. We also present essential characterization tools for obtaining dynamic and structural information, including the visualization cyclic peptide assembly into nanotubes (AFM, TEM) as well as the use of fluorescence microscopy
PB Springer
SN 978-1-0716-1689-5
YR 2022
FD 2022
LK http://hdl.handle.net/10347/29373
UL http://hdl.handle.net/10347/29373
LA eng
NO Méndez-Ardoy, A., Insua, I., Granja, J.R., Montenegro, J. (2022). Cyclization and Self-Assembly of Cyclic Peptides. In: Coppock, M.B., Winton, A.J. (eds) Peptide Macrocycles. Methods in Molecular Biology, vol 2371. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1689-5_24
NO Part of the Methods in Molecular Biology book series (MIMB,volume 2371)
DS Minerva
RD 4 may 2026