RT Journal Article
T1 Neurocognitive effects of binge drinking on verbal episodic memory. An ERP study in university students
A1 Rodríguez Holguín, Socorro
A1 Folgueira Ares, Rocío
A1 Crego Barreiro, Manuel Alberto
A1 López Caneda, Eduardo Guillermo
A1 Corral Varela, María Montserrat
A1 Doallo Pesado, Sonia
K1 Binge drinking
K1 Alcohol
K1 University students
K1 Verbal episodic memory
K1 Memory
K1 Event-related potentials
K1 Consumo intensivo de alcohol
K1 Estudantes
K1 Mozos/as
K1 Memoria
K1 Memoria episódica verbal
K1 Potenciais evocados
AB Background: Verbal memory may be affected by engagement in alcohol binge drinking during youth, according to the findings of neuropsychological studies. However, little is known about the dynamics of the neural activity underlying this cognitive process in young, heavy drinkers.Aims: To investigate brain event-related potentials associated with cued recall from episodic memory in binge drinkers and controls.Methods: Seventy first-year university students were classified as binge drinkers (32: 17 female) or controls (38: 18 female). The participants completed a verbal paired associates learning task during electroencephalogram (EEG) recording. ERPs elicited by old and new word pairs were extracted from the cued-recall phase of the task by using Principal Component Analysis. Subjects also performed a standardized neuropsychological verbal learning test.Results: Two of the three event-related potentials components indicating old/new memory effects provided evidence for anomalies associated with binge drinking. The old/new effects were absent in the binge drinkers in the two subsequent posterior components, identified with the late parietal component and the late posterior negativity The late frontal component revealed similar old/new effects in both groups. Binge drinkers showed similar behavioural performance to controls in the verbal paired associates task, but performed poorly in the more demanding short-term cued-recall trial of a neuropsychological standardized test.Conclusion: Event-related potentials elicited during a verbal cued-recall task revealed differences in brain functioning between young binge drinkers and controls that may underlie emergent deficits in episodic memory linked to alcohol abuse. The brain activity of binge drinkers suggests alterations in the hippocampal - posterior parietal cortex circuitry subserving recognition and recollection of the cue context and generation of the solution, in relation to verbal information shallowly memorised.
PB Frontiers Media
YR 2023
FD 2023-02-07
LK http://hdl.handle.net/10347/30022
UL http://hdl.handle.net/10347/30022
LA eng
NO Rodríguez Holguín, S., Folgueira-Ares, R., Crego, A., López-Caneda, E., Corral, M., Cadaveira, F. e Doallo, S. (2023). Neurocognitive effects of binge drinking on verbal episodic memory. An ERP study in university students. Frontiers in Pharmacology, 14, 1034248. https://doi.org/10.3389/fphar.2023.1034248
NO This work was supported by grants PID 2020-113487RB-100, funded by MCIN/AEI/10.13039/501100011033; PSI2011-22575, funded by MCIN, and GRC ED431C 2021/08, funded by the Department of I + D of the Regional Government, Xunta de Galicia
DS Minerva
RD 23 abr 2026