RT Journal Article
T1 Anion recognition and induced self-assembly of an alpha,gamma-cyclic peptide to form spherical clusters
A1 Rodríguez-Vázquez, Nuria
A1 Amorín López, Manuel
A1 Granja Guillán, Juan Ramón
A1 Alfonso, Ignacio
K1 Anionrecognition
K1 Cyclic peptide
K1 Self-assembling
K1 Supramolecular chemistry
K1 Transport
AB A cyclic octapeptide composed of hydroxy-functionalized γ-amino acids folds in a "V-shaped" conformation that allows the selective recognition of anions such as chloride, nitrate, and carbonate. The process involves the simultaneous self-assembly of six peptide subunits and the recognition of four anions to form a tetrahedral structure, in which the anions are located at the corners of the resulting structure. Each anion is coordinated to three different peptides. The structure was fully characterized by several techniques, including NMR spectroscopy and X-ray diffraction, and the material was able to facilitate the transmembrane transport of chloride ions
PB Wiley
SN 1433-7851
YR 2016
FD 2016-03-21
LK http://hdl.handle.net/10347/16736
UL http://hdl.handle.net/10347/16736
LA eng
NO Rodríguez-Vázquez, N., García-Fandiño, R., Amorín, M., & Granja, J. (2016). Anion recognition self-assembly α,γ-cyclic peptide to form spherical clusters. Angewandte Chemie internationa edition,55(14):4504-8. Doi: 10.1002/anie.201511857
NO This work was supported by the Spanish Ministry of Economy and Competitivity (MINECO) and the ERDF [CTQ2013-43264-R, CTQ2012-38543-C03-03], and by the Xunta de Galicia and the ERDF (GPC2013-039 and EM2014/011). N. R.-V. thanks MINECO for her FPU contract. We also thank ORFEO-CINCA network and MINECO (CTQ2014-51912-REDC). Technical support from the Unidade de Raios X, RIADT, USC, and especially to Antonio L. Llamas-Saiz is gratefully acknowledged
DS Minerva
RD 24 abr 2026