RT Journal Article T1 Symptoms of Depression, Anxiety, and Stress and Prevalence of Major Depression and Its Predictors in Female University Students A1 Blanco Seoane, Vanessa A1 Salmerón Palenzuela, María del Mar A1 Otero Otero, Patricia A1 Vázquez González, Fernando Lino K1 Depression K1 Anxiety K1 Stress K1 Major depression K1 Predictors K1 University students AB Depression, anxiety and stress are increasingly concerning phenomena in our society, with serious consequences on physical and mental health. The repercussions may be particularly devastating in particular population subgroups, such as female university students. The purpose of this study was to determine the levels of depression, anxiety, and stress and the prevalence of depression and associated factors, in Spanish university women. A cross-sectional study was conducted with a random sample of 871 students from the Santiago de Compostela University (mean age 20.7 years, SD = 2.8). Information was collected on sociodemographic and academic characteristics; symptoms of depression, anxiety, and stress; diagnosis of major depression; optimism, resilience, social support, life engagement, and five personality domains, using validated instruments. Of the participants, 18.1%, 22.8% and 13.5% presented with severe/very severe levels of depression, anxiety and stress, respectively. A total of 12.9% had major depression. Higher life engagement was associated with lower risk of depression (OR = 0.92, 95% CI 0.87–0.98), while higher levels of neuroticism (OR = 1.20, 95% CI, 1.12–1.28) and openness to experience (OR = 1.08, 95% CI, 1.02–1.14) were associated with greater risk. These findings reveal an alarming percentage of female university students who experience major depression and severe/very severe stress PB MDPI YR 2021 FD 2021 LK 10.3390/ijerph18115845 LK http://hdl.handle.net/10347/26759 UL 10.3390/ijerph18115845 UL http://hdl.handle.net/10347/26759 LA eng NO Int. J. Environ. Res. Public Health 2021, 18(11), 5845; https://doi.org/10.3390/ijerph18115845 NO This study was funded by the University of Santiago de Compostela (2019-PU005) DS Minerva RD 23 abr 2026