RT Journal Article T1 Quality of life in patients with fibromyalgia: contributions of disease symptoms, lifestyle and multi-medication A1 Fernández-Feijoo, Fátima A1 Samartín Veiga, Noelia A1 Carrillo de la Peña, María Teresa K1 Chronic pain K1 Quality of life K1 Lifestyle K1 Anxiety K1 Depression K1 Multi-medication AB Fibromyalgia (FM) is a disease characterized by the presence of chronic andwidespread musculoskeletal pain, which causes a high negative impact onthe quality of life (QoL). Although there are many studies about the QoLof patients with FM, it is unknown which variables have a main influenceon it. Therefore, in the present study, we aimed to determine which FMsymptoms predict a worse QoL and also to establish whether lifestyle andmulti-medication are associated to QoL.We assessed a sample of 134 womenwith FM using a semi-structured clinical interview to explore lifestyle (diet,exercise, smoking) and medication use, and questionnaires to cover the mainsymptoms of this disease and QoL (SF-36).We found that the patients with FMhad a poor QoL, being “physical pain” and “vitality” the most affected domains.A linear regression analysis showed that depression and anxiety assessedby HADS were the FM symptoms which most significantly predicted QoL,explaining 49% of the variance. Concerning lifestyle/medication influences,we found that multiple drug treatment and smoking also predicted a worseQoL (14%). Moreover, patients who practiced exercise regularly showed betterQoL than patients who did not (regardless of the severity of FM). Thus,our results suggest that treatment strategies to improve QoL in FM shouldbe focused on improving psychological distress, promoting regular exerciseand reducing smoking and multi-medication. The data highlights the role ofpositive self-management practices to improve QoL in FM PB Frontiers Media YR 2022 FD 2022 LK http://hdl.handle.net/10347/29896 UL http://hdl.handle.net/10347/29896 LA eng NO Fernandez-Feijoo F, Samartin-Veiga N and Carrillo-de-la-Peña MT (2022) Quality of life in patients with fibromyalgia: contributions of disease symptoms, lifestyle and multi-medication. Front. Psychol. 13:924405 NO This study has been funded by the Spanish Government (Ministerio de Economía y Competitividad; ref PSI2016-75313- R) and Galician Government (IDT Plan. Grant 2021-PG011). In addition, NS-V was supported by a grant from the Spanish Government (Ministerio de Economía y Competitividad; grant number: BES-2017-082684) DS Minerva RD 25 abr 2026