RT Journal Article
T1 Quercetin and related chromenone derivatives as monoamine oxidase inhibitors: targeting neurological and mental disorders
A1 Dhiman, Priyanka
A1 Malik, Neelam
A1 Sobarzo Sánchez, Eduardo Marcelo
A1 Uriarte Villares, Eugenio
A1 Khatkar, Anurag
K1 Monoamine oxidase
K1 Neurodegenerative disorder
K1 Mental disorders
K1 Quercetin
K1 Flavonoids
K1 Monoamine oxidase inhibitors
K1 In-silico design
AB Monoamine oxidase inhibitions are considered as important targets for the treatmentof depression, anxiety, and neurodegenerative disorders, including Alzheimer’s and Parkinson’sdiseases. This has encouraged many medicinal chemistry research groups for the development ofmost promising selective monoamine oxidase (MAO) inhibitors. A large number of plant isolatesalso reported for significant MAO inhibition potential in recent years. Differently substitutedflavonoids have been prepared and investigated as MAO-A and MAO-B inhibitors. Flavonoidscaffold showed notable antidepressant and neuroprotective properties as revealed by various andestablished preclinical trials. The current review made an attempt to summarizing and criticallyevaluating the new findings on the quercetin and related flavonoid derivatives functions as potentMAO isoform inhibitors
PB MDPI
YR 2019
FD 2019
LK http://hdl.handle.net/10347/22549
UL http://hdl.handle.net/10347/22549
LA eng
NO Dhiman, P., Malik, N., Sobarzo-Sánchez, E., Uriarte, E., Khatkar, A. (2019). Quercetin and related chromenone derivatives as monoamine oxidase inhibitors: targeting neurological and mental disorders. Molecules  24(3), 418; doi: 10.3390/molecules24030418
DS Minerva
RD 29 abr 2026