RT Journal Article
T1 An overview on the relationship between residential radon and lung cancer: what we know and future research
A1 Ruano Raviña, Alberto
A1 Martín Gisbert, Lucía
A1 Kelsey, Karl
A1 Pérez Ríos, Mónica
A1 Candal Pedreira, Cristina
A1 Rey Brandariz, Julia
A1 Varela Lema, María Leonor
K1 Radon 
K1 Lung cancer 
K1 Exposure 
K1 Molecular pathways
AB We aim to provide an overview of the research available on indoor radon and lung cancer, with a special focus on Spanish investigations. Early studies on underground miners established the link between radon and lung cancer, which was later confirmed for the general population by residential case–control studies. Spain contributed with extensive evidence, including 5 multicentric, hospital-based, case–control studies in the last 30 years, exploring diverse aspects, such as radon's effect on never-smokers, molecular pathways linking radon exposure to lung cancer risk, survival rates, mortality burden, and occupational exposure. There is a well-established causal association between radon with lung cancer. Despite pioneering research performed in our country by the Galician Radon Laboratory, particularly on driver genes, the evidence on the potential molecular pathways which makes radon a carcinogen is sparse. Also, relevant questions on the potential association of radon exposure with the induction of other diseases are still pending
PB Springer
YR 2023
FD 2023-08-23
LK http://hdl.handle.net/10347/31200
UL http://hdl.handle.net/10347/31200
LA eng
NO Clin Transl Oncol 25, 3357–3368 (2023)
NO Open Access funding provided thanks to the CRUE-CSIC  agreement with Springer Nature. This research was funded by Instituto  de Salud Carlos III ISCIIII/PI21/01081/co-funded by the European  Union. This research is part of Lucia Martin-Gisbert Ph.D. thesis
DS Minerva
RD 28 abr 2026