RT Dissertation/Thesis
T1 Sources of Genomic Instability in the Cancer Genome
A1 Santamarina García, Martín
K1 cancer
K1 genome
K1 somatic
K1 genomic instability
K1 bioinformatics
K1 retrotransposition
AB Cancer is commonly referred to as a complex group of genetic diseases, encompassing over 100 disorders that affect multiple cell types and tissues in humans and many other multicellular organisms. At its core, cancer is characterized by uncontrolled cell proliferation, driven by populations of transformed tumour cells undergoing evolutionary changes. In humans, cancer is a leading global cause of death, responsible for over 8 million deaths each year. Notably, more than 90% of cancer-related deaths are linked to metastasis, a process through which tumour cells disseminate through the circulatory and lymphatic systems and invade distant organs.
YR 2025
FD 2025
LK https://hdl.handle.net/10347/39866
UL https://hdl.handle.net/10347/39866
LA eng
DS Minerva
RD 24 abr 2026