RT Journal Article
T1 Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic movements
A1 Pischedda, Sara
A1 Barral Arca, Ruth
A1 Gómez Carballa, Alberto
A1 Pardo Seco, Jacobo José
A1 Catelli, M.L.
A1 Álvarez Iglesias, Vanesa
A1 Cárdenas Paredes, Jorge Mario
A1 Nguyen, N.D.
A1 Ha, H.H.
A1 Le, A.T.
A1 Martinón Torres, Federico
A1 Vullo, Carlos
A1 Salas Ellacuriaga, Antonio
AB The territory of present-day Vietnam was the cradle of one of the world’s earliest civilizations, and one of the first world regions to develop agriculture. We analyzed the mitochondrial DNA (mtDNA) complete control region of six ethnic groups and the mitogenomes from Vietnamese in The 1000 Genomes Project (1000G). Genome-wide data from 1000G (~55k SNPs) were also investigated to explore different demographic scenarios. All Vietnamese carry South East Asian (SEA) haplotypes, which show a moderate geographic and ethnic stratification, with the Mong constituting the most distinctive group. Two new mtDNA clades (M7b1a1f1 and F1f1) point to historical gene flow between the Vietnamese and other neighboring countries. Bayesian-based inferences indicate a time-deep and continuous population growth of Vietnamese, although with some exceptions. The dramatic population decrease experienced by the Cham 700 years ago (ya) fits well with the Nam tiến (“southern expansion”) southwards from their original heartland in the Red River Delta. Autosomal SNPs consistently point to important historical gene flow within mainland SEA, and add support to a main admixture event occurring between Chinese and a southern Asian ancestral composite (mainly represented by the Malay). This admixture event occurred ~800 ya, again coinciding with the Nam tiến.
PB Nature Publishing Group
YR 2017
FD 2017
LK http://hdl.handle.net/10347/22672
UL http://hdl.handle.net/10347/22672
LA eng
NO Pischedda, S., Barral-Arca, R., Gómez-Carballa, A. et al. Phylogeographic and genome-wide investigations of Vietnam ethnic groups reveal signatures of complex historical demographic movements. Sci Rep 7, 12630 (2017). https://doi.org/10.1038/s41598-017-12813-6
NO This study received support from the Instituto de Salud Carlos III (Proyecto de Investigación en Salud, Acción Estratégica en Salud: project GePEM ISCIII/PI16/01478/Cofinanciado FEDER) (AS) and project ReSVinext ISCIII/PI16/01569/Cofinanciado FEDER (FMT); Consellería de Sanidade, Xunta de Galicia (RHI07/2-intensificación actividad investigadora, PS09749 and 10PXIB918184PR), Instituto de Salud Carlos III (Intensificación de la actividad investigadora 2007–2012, PI16/01569), Fondo de Investigación Sanitaria (FIS; PI070069/PI1000540) del plan nacional de I+D+I and “fondos FEDER” (FMT), and 2016-PG071 Consolidación e Estructuración REDES 2016GI-1344 G3VIP (Grupo Gallego de Genética Vacunas Infecciones y Pediatría, ED341D R2016/021) (AS and FMT)
DS Minerva
RD 30 abr 2026