RT Dissertation/Thesis T1 Mathematical models of tumor response in advanced radiotherapy techniques A1 González Crespo, Isabel K1 Mathematical models K1 radiotherapy K1 FLASH-RT K1 radioimmunotherapy AB Radiotherapy is a cancer treatment that consists of irradiating tumors to eliminate tumor cells while maintaining the dose on neighbor organs/tissues within tolerance levels. Mathematical models predict the efficacy and toxicity of radiotherapy, assisting in designing more effective and less toxic treatments. This thesis aims to design mathematical models of tumor response to advanced radiotherapies by using ordinary (ODEs), partial (PDEs), delay (DDEs), and impulsive differential equations (IDEs). The focus is on radioimmunotherapy and FLASH radiotherapy, which involve biological mechanisms that require the development of novel mathematical models, as the existing ones for conventional radiotherapy are not directly applicable. YR 2024 FD 2024 LK https://hdl.handle.net/10347/39601 UL https://hdl.handle.net/10347/39601 LA eng DS Minerva RD 29 abr 2026