RT Journal Article
T1 In-Vial Micro-Matrix-Solid Phase Dispersion for the Analysis of Fragrance Allergens, Preservatives, Plasticizers, and Musks in Cosmetics
A1 Celeiro Montero, María
A1 Lamas Castro, Juan Pablo
A1 Llompart Vizoso, María del Pilar
A1 García Jares, Carmen María
K1 Cosmetics
K1 Micro-matrix solid-phase dispersion
K1 Fragrance allergens
K1 Preservatives
K1 Plasticizers
K1 Musks
K1 Gas chromatography-mass spectrometry (GC-MS)
AB Fragrance allergens, preservatives, plasticizers, and synthetic musks are usually present in cosmetic and personal care products formulations and many of them are subjected to use restrictions or labeling requirements. Matrix solid-phase dispersion (MSPD) is a very suitable analytical technique for the extraction of these compounds providing a simple, low cost sample preparation, and the possibility of performing both extraction and clean-up in one step, reducing possible contamination and analyte losses. This extraction technique has been successfully applied to many cosmetics ingredients allowing obtaining quantitative recoveries. A new very simple micro-MSPD procedure performing the disruption step in a vial is proposed for the gas chromatography-mass spectrometry (GC-MS) analysis of 66 chemicals usually present in cosmetics and personal care products. The method was validated showing general recoveries between 80% and 110%, relative standard deviation (RSD) values lower than 15%, and limits of detection (LODs) below 30 ng·g−1. The validated method was applied to a broad range of cosmetics and personal care products, including several products intended for baby care
PB MDPI
YR 2014
FD 2014
LK http://hdl.handle.net/10347/23705
UL http://hdl.handle.net/10347/23705
LA eng
NO Celeiro, M.; Lamas, J.P.; Llompart, M.; Garcia-Jares, C. In-Vial Micro-Matrix-Solid Phase Dispersion for the Analysis of Fragrance Allergens, Preservatives, Plasticizers, and Musks in Cosmetics. Cosmetics 2014, 1, 171-201
NO This research was supported by Fondo Europeo de Desarrollo Regional (FEDER) funds and projects CTQ 2013-46545-P (Ministerio de Economía y Competitividad, Spain) and CN 2012/299 (Research Groups Consolidation Program, Xunta de Galicia)
DS Minerva
RD 24 abr 2026