RT Journal Article
T1 Multianalyte method for the determination of regulated, emerging and modified mycotoxins in milk: QuEChERS extraction followed by UHPLC–MS/MS analysis
A1 González Jartín, Jesús María
A1 Rodríguez Cañás, Inés
A1 Alfonso Rancaño, María Amparo
A1 Sáinz Oses, María Jesús
A1 Rodríguez Vieytes, Mercedes
A1 Gomes, Ana
A1 Ramos, Isabel
A1 Botana López, Luis Miguel
K1 Mycotoxin
K1 Milk
K1 QuEChERS
K1 UHPLC-MS/MS
AB A simple method for the quantification of 40 mycotoxins in milk was developed. This method is based on a QuEChERS extraction followed by the ultra-high liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) detection, and allows the simultaneous analysis of regulated, emerging, and modified mycotoxins. A sample treatment procedure was optimized to include a concentration step for the analysis of some compounds such as aflatoxin M1. The method was in-house validated in terms of limits of detection (LODs), limits of quantification (LOQs), linearity, recoveries, and precision. LOQs lower than 10 ng/mL were obtained, and recoveries ranged from 61% to 120% with a precision, expressed as the relative standard deviation, lower than 15%. Therefore, acceptable performance characteristics were obtained fulfilling European regulations. The method was successfully applied for the quantification of mycotoxins in raw milk. It can be highlighted high occurrence of beauvericin and enniatins were found in low amounts.
PB Elsevier
SN 0308-8146
YR 2021
FD 2021-09-15
LK https://hdl.handle.net/10347/44562
UL https://hdl.handle.net/10347/44562
LA eng
NO Food Chemistry Volume 356, 15 September 2021, 129647
NO The research leading to these results has received funding from the following FEDER cofunded-grants. From Conselleria de Cultura, Educacion e Ordenación Universitaria, Xunta de Galicia, 2017 GRC GI-1682 (ED431C 2017/01). From Ministerio de Ciencia e Innovación IISCIII/PI19/001248. From European Union Interreg AlertoxNet EAPA-317-2016, Interreg Agritox EAPA-998-2018, and H2020 778069-EMERTOX.
DS Minerva
RD 19 abr 2026