RT Journal Article T1 An Ontology-Based Interpretable Fuzzy Decision Support System for Diabetes Diagnosis A1 El-Sappagh, Shaker A1 Alonso Moral, José María A1 Ali, Farman A1 Ali, Amjad A1 Jang, Jun-Hyeog A1 Kwak, Kyung-Sup K1 Diabetes K1 Cognition K1 Ontologies K1 Medical diagnostic imaging K1 Diseases K1 Semantics AB Diabetes is a serious chronic disease. The importance of clinical decision support systems (CDSSs) to diagnose diabetes has led to extensive research efforts to improve the accuracy, applicability, interpretability, and interoperability of these systems. However, this problem continues to require optimization. Fuzzy rule-based systems are suitable for the medical domain, where interpretability is a main concern. The medical domain is data-intensive, and using electronic health record data to build the FRBS knowledge base and fuzzy sets is critical. Multiple variables are frequently required to determine a correct and personalized diagnosis, which usually makes it difficult to arrive at accurate and timely decisions. In this paper, we propose and implement a new semantically interpretable FRBS framework for diabetes diagnosis. The framework uses multiple aspects of knowledge-fuzzy inference, ontology reasoning, and a fuzzy analytical hierarchy process (FAHP) to provide a more intuitive and accurate design. First, we build a two-layered hierarchical and interpretable FRBS; then, we improve this by integrating an ontology reasoning process based on SNOMED CT standard ontology. We incorporate FAHP to determine the relative medical importance of each sub-FRBS. The proposed system offers numerous unique and critical improvements regarding the implementation of an accurate, dynamic, semantically intelligent, and interpretable CDSS. The designed system considers the ontology semantic similarity of diabetes complications and symptoms concepts in the fuzzy rules' evaluation process. The framework was tested using a real data set, and the results indicate how the proposed system helps physicians and patients to accurately diagnose diabetes mellitus PB IEEE YR 2018 FD 2018 LK http://hdl.handle.net/10347/17725 UL http://hdl.handle.net/10347/17725 LA eng NO El-Sappagh, S., Alonso, J., Ali, F., Ali, A., Jang, J., & Kwak, K. (2018). An Ontology-Based Interpretable Fuzzy Decision Support System for Diabetes Diagnosis. IEEE Access, 6, 37371-37394. doi: 10.1109/access.2018.2852004 NO This work was supported by National Research Foundation of Korea-Grant funded by the Korean Government (Ministry of Science, ICT and Future Planning)-NRF-2017R1A2B2012337) DS Minerva RD 28 abr 2026