RT Journal Article
T1 Pain, oedema and trismus responses following photobiomodulation therapy immediately after lower third molar extraction: results of a randomized, doble-blind and split mouth clinical trial
A1 Vianna Camolesi, Gisela Cristina
A1 El Kattan, Ahmed Samir
A1 López-López, José
A1 Blanco Carrión, Andrés
A1 García García, Abel
A1 Gándara Vila, Pilar
A1 Pérez-Sayáns García, Mario
K1 Photobiomodulation therapy
K1 Pain management
K1 Postoperative facial oedema
K1 Trismus reduction
K1 Lower third molar extraction
AB ObjectivesTo assess the impact of photobiomodulation therapy in pain, facial oedema, and trismus mitigation in the postoperative period after lower third molar extractions.MethodsWe conducted a comparison between active photobiomodulation and simulated photobiomodulation after both lower third molars extraction in the same patients, within a double-center clinical trial. The role of photobiomodulation was evaluated based on pain, measured using the VAS scale. Oedema and trismus, assessed through millimetric measurements. Additionally, analgesic consumption was monitored during the 7-day's postoperative period. The study adhered to the CONSORT checklist and was registered on the ClinicalTrials (NCT05255731). The Levene test was used to assess precision (α=0.05), and statistical analysis was performed using Jamovi software. Paired t-tests or the Wilcoxon test were employed to analyze the primary and secondary outcomes.ResultsThe study included 83 patients and 166 randomization units. The study group showed a significant reduction in pain at all evaluation times (P < .01), as well as reductions in facial oedema and trismus on postoperative days 2 and 7 (P < .01). A significant difference in analgesic use was observed on all days, except on the seventh postoperative day.ConclusionThe photobiomodulation protocol, using an 808 nm, 100 mW Ga-Al-As diode laser, applied both intraorally and extraorally in a single 30 seconds (3 Joules/per point) postoperative session, significantly reduced pain, oedema, and trismus following mandibular third molar extraction, particularly on postoperative days 2 and 7.Clinical SignificancePhotobiomodulation can be an effective complementary therapy for reducing pain, facial oedema, and trismus in patients after lower third molar extraction.
PB Elsevier
SN 1532-3382
YR 2025
FD 2025-03
LK https://hdl.handle.net/10347/40798
UL https://hdl.handle.net/10347/40798
LA eng
NO Camolesi, G. C. V., El Kattan, A. S., Lopez-Lopez, J., Blanco-Carrión, A., García-García, A., Gándara-Vila, P., Pérez-Sayáns, M. (2025). Pain, oedema and trismus responses following photobiomodulation therapy immediately after lower third molar extraction: Results of a randomized, doble-blind and split mouth clinical trial.” Journal of Evidence-Based Dental Practice”, 25(1), 102080. https://doi.org/10.1016/j.jebdp.2024.102080
DS Minerva
RD 9 may 2026