RT Journal Article
T1 Multi-year inter-laboratory exercises for the analysis of illicit drugs and metabolites in wastewater: Development of a quality control system
A1 Nuijs, Alexander L. N. van
A1 Lai, Foon Yin
A1 Been, Frederic
A1 Andrés-Costa, María Jesús
A1 Barron, Leon
A1 Baz-Lomba, Jose Antonio
A1 Berset, Jean-Daniel
A1 Benaglia, Lisa
A1 Bijlsma, Lubertus
A1 Burgard, Daniel A.
A1 Castiglioni, Sara
A1 Christophoridis, Christophoros E.
A1 Covaci, Adrian
A1 Voogt, Pim de
A1 Emke, Erik
A1 Fatta-Kassinos, Despo
A1 Fick, Jerker
A1 Hernández, Félix
A1 Gerber, Cobus
A1 González Mariño, Iria
A1 Grabic, Roman
A1 Gunnar, Teemu
A1 Kannan, Kurunthachalam
A1 Karolak, Sara
A1 Kasprzyk-Hordern, Barbara
A1 Kokot, Zenon
A1 Krizman-Matasic, Ivona
A1 Li, Angela
A1 Li, Xiqing
A1 Löve, Arndís S.C.
A1 López de Alda, Miren
A1 McCall, Ann-Kathrin
A1 Meyer, Markus R.
A1 Oberacher, Herbert
A1 O'Brien, Jake
A1 Quintana Álvarez, José Benito
A1 Reid, Malcolm J.
A1 Schneider, Serge
A1 Sadler Simoes, Susana
A1 Thomaidis, Nikolaos S.
A1 Thomas, Kevin V.
A1 Yargeau, Viviane
A1 Ort, Christoph
K1 Illicit drugs
K1 Wastewater
K1 Inter-laboratory testing
K1 Wastewater-based epidemiology
K1 Quality assurance
AB Thirty-seven laboratories from 25 countries present the development of an inter-laboratory testing scheme for the analysis of seven illicit drug residues in standard solutions, tap- and wastewater. Almost 10 000 concentration values were evaluated: triplicates of up to five samples and 26 laboratories per year. The setup was substantially improved with experiences gained across the six repetitions (e.g. matrix type, sample conditions, spiking levels). From this, (pre-)analytical issues (e.g. pH adjustment, filtration) were revealed for specific analytes which resulted in formulation of best-practice protocols for inter-laboratory setup and analytical procedures. The results illustrate the effectiveness of the inter-laboratory setup to assess laboratory performance in the framework of wastewater-based epidemiology. The exercise proved that measurements of laboratories were of high quality (>80% satisfactory results for six out of seven analytes) and that analytical follow-up is important to assist laboratories in improving robustness of wastewater-based epidemiology results
PB Elsevier
SN 0165-9936
YR 2018
FD 2018-03-22
LK http://hdl.handle.net/10347/17857
UL http://hdl.handle.net/10347/17857
LA eng
NO Van Nuijs et al. Multi-year interlaboratory exercises for the analysis of illicit drugs and metabolites in wastewater: development of a quality control system  Trends in Analytical Chemistry, 2018, 103, 34-43. Doi: 10.1016/j.trac.2018.03.009
NO This is the postprint (accepted manuscript) version of the article published in Trends in Analytical Chemistry.https://doi.org/10.1016/j.trac.2018.03.009
NO This article is based upon work from COST Action ES1307 supported by COST (European Cooperation in Science and Technology). We wish to acknowledge EMCDDA and Yeonsuk Ryu for support in the organization of the scheme and assistance in the preparation of the test samples, respectively. The following funding sources are acknowledged: the Research Foundation – Flanders (FWO) (Grant number: 1285216N), the Spanish Ministry of Economy, Industry and Competitiveness, the Generalitat Valenciana, Xunta de Galicia, Stavros Niarchos Foundation, Office for Combating Narcotic Drug Abuse of the Government of the Republic of Croatia, EU FP7 project SOLUTIONS (603437), the Government of Catalonia, the Natural Sciences and Engineering Research Council of Canada (NSERC), Ministry of Education, Youth and Sports of the Czech Republic (projects CENAKVA and CENAKVA II), EU Marie Skłodowska-Curie Fellowship (APOLLO 749845) and the Swiss National Science Foundation (SNSF, P2LAP2_164892)
DS Minerva
RD 29 abr 2026