RT Dissertation/Thesis
T1 New strategies for the prevention and treatment of complications associated with diabetes mellitus
A1 Bendicho Lavilla, Carlos
K1 Diabetes mellitus
K1 Implants
K1 Subcutaneous administration
AB Diabetes mellitus has emerged as one of the most prevalentchronic diseases of the 21st century with seriouscomplications worsening its progression. This doctoral thesis isdivided into four chapters focused on improving thetreatment of complications associated with diabetes mellitus. Inthe first chapter, the subcutaneous administration ofbiopharmaceuticals is adressed as an effective and patientpreferredalternative to intravenous infusions. In the secondchapter, supercritical foaming technology was utilised tomanufacture PLGA implants loaded with dexamethasone andbevacizumab. The third chapter develops a drug deliverysystem to enhance the penetration of antifungal drugs into nailswith onychomycosis. The fourth chapter develops an inertcoating for in vitro testing with 3D printed devices.
YR 2024
FD 2024
LK http://hdl.handle.net/10347/33516
UL http://hdl.handle.net/10347/33516
LA eng
DS Minerva
RD 29 abr 2026