RT Journal Article
T1 The Toxicity Exerted by the Antibiotic Sulfadiazine on the Growth of Soil Bacterial Communities May Increase over Time
A1 Santás Miguel, Vanesa
A1 Rodríguez González, Laura
A1 Núñez Delgado, Avelino
A1 Díaz Raviña, Montserrat
A1 Arias Estévez, Manuel
A1 Fernández Calviño, David
K1 Leucine incorporation
K1 Risk assessment
K1 Sulfonamide
K1 Veterinary
K1 Microbial community
AB The toxicity exerted by the antibiotic sulfadiazine on the growth of soil bacterial communities was studied in two agricultural soils for a period of 100 days. In the short-term (2 days of incubation), the effect of sulfadiazine on bacterial growth was low (no inhibition or inhibition <32% for a dose of 2000 mg·kg−1). However, sulfadiazine toxicity increased with time, achieving values of 40% inhibition, affecting bacterial growth in both soils after 100 days of incubation. These results, which were here observed for the first time for any antibiotic in soil samples, suggest that long-term experiments would be required for performing an adequate antibiotics risk assessment, as short-term experiments may underestimate toxicity effects
PB MDPI
YR 2020
FD 2020
LK http://hdl.handle.net/10347/24029
UL http://hdl.handle.net/10347/24029
LA eng
NO Santás-Miguel, V.; Rodríguez-González, L.; Núñez-Delgado, A.; Díaz-Raviña, M.; Arias-Estévez, M.; Fernández-Calviño, D. The Toxicity Exerted by the Antibiotic Sulfadiazine on the Growth of Soil Bacterial Communities May Increase over Time. Int. J. Environ. Res. Public Health 2020, 17, 8773
NO This study has been funded by the Spanish Ministry of Economy and Competitiveness through the projects CGL2015-67333-C2-1-R and -2-R (FEDER Funds), and by Xunta de Galicia via CITACA Strategic Partnership (ED431E 2018/07) and BV1 research group (ED431C 2017/62-GRC). David Fernández Calviño holds a Ramón y Cajal contract (RYC-2016-20411) financed by the Spanish Ministry of Economy Industry and Competitiveness. Vanesa Santás Miguel holds a pre-doctoral fellowship founded by the University of Vigo
DS Minerva
RD 24 abr 2026