RT Journal Article T1 Technological feasibility and environmental assessment of polylactic acid-nisin-based active packaging A1 Arias Calvo, Ana A1 Feijoo Costa, Gumersindo A1 Moreira Vilar, María Teresa K1 Active packaging K1 Functional film K1 PLA-nisin K1 Life cycle assessment AB The new consumption patterns based on the “use and throw away” trend has led to an increase in the production of petroleum-based plastics for their application as food packaging films, leading to significant environmental impacts. In the search for alternatives to conventional plastics, polylactic acid (PLA) stands out due to its renewable origin, its mechanical properties and its biodegradability potential. In this regard, this manuscript addresses the large-scale simulation of a bio-technological process for the valorization of wheat straw residues for the co-production of nisin and lactic acid through a batch-type fermentation process. Subsequently, lactic acid will be used for the production of PLA films, to which nisin will be applied to convert them into functional antimicrobial films. To assess the degree of environmental impacts and sustainability of this biotechnological process, Life Cycle Assessment, considering a cradle-to-gate approach, and Greenness Grid methodologies have been applied. The environmental profiles obtained showed that the pre-treatment and downstream stages are the ones leading to the highest impact, being the energy requirements the main hot spots. Moreover, seeking an environmental communication perspective, useful for researchers and stakeholders, the Green Index indicator value obtained leads to the consideration of a potentially sustainable process PB Elsevier YR 2022 FD 2022 LK http://hdl.handle.net/10347/29144 UL http://hdl.handle.net/10347/29144 LA eng NO Sustainable Materials and Technologies 33 (2022) e00460 NO This research has been financially supported by the European project iFermenter (Grant Agreement 79057). iFermenter is a project funded under the “Bio-Based Industries Joint Undertaking under the European Union's Horizon 2020 research and innovation programme”. The authors belong to the Galician Competitive Research Group (GRC ED431C 2017/29) and to the Cross-disciplinary Research in Environmental Technologies (CRETUS Research Center, ED431E 2018/01) DS Minerva RD 27 abr 2026