RT Journal Article T1 Bisphenol A in food as a result of its migration from food packaging A1 Vilarinho, F. A1 Sendón García, Raquel A1 Kellen, A. van der A1 Vaz, M.F. A1 Silva, A. Sanches K1 Bisphenol A K1 Chromatography K1 Food packaging K1 Migration K1 Polycarbonate K1 Epoxy resins AB Background : Bisphenol A (BPA) is mainly used in the production of polycarbonate, a material with high durability and strength. This chemical is also used in the production of epoxy resins, applied in the coating of metal surfaces in contact with food. Moreover, it is employed in thermal paper. BPA has been widely reported by the media, being the aim of diverse scientific studies, since it is a xenoestrogen with a chemical structure identical to that of 17β-estradiol, which allows it to interact with human estrogen receptors. Approach: BPA monitoring is essential to avoid the potential health risk of the population, the European Union has recently updated the specific migration limit (SML) for BPA at 0.05 mg/kg of food. The present paper is the result of a vast literature review carried out to set up the state of the art related to BPA, concerning the analytical methodologies used for its determination and the levels detected in food as result of its migration from food contact materials. Conclusions : It was verified that the most used methodologies for the determination of BPA by chromatographic methods are high or ultra-highperformance liquid chromatography (HPLC or UHPLC) coupled to fluorescence detector (FL) or mass spectrometry (MS) and gas chromatography coupled with MS (GC-MS). Regarding the levels of migration determined in different types of food contact materials, it was found that, despite the great majority of studies showed positive samples, none of them exceeded the value of SML established by the European Union at the time of the studies. PB Elsevier SN 0924-2244 YR 2019 FD 2019 LK https://hdl.handle.net/10347/39433 UL https://hdl.handle.net/10347/39433 LA eng NO Vilarinho, F., Sendón, R., van der Kellen, A., Vaz, M. F., & Silva, A. S. (2019). Bisphenol A in food as a result of its migration from food packaging. Trends in Food Science & Technology, 91, 33–65. https://doi.org/10.1016/j.tifs.2019.06.012 NO This work was supported by FCT, through IDMEC, under LAETA, project UID/EMS/50022/2019 NO This work was supported by National Institute of Health Dr. Ricardo Jorge through the project “Development of methodologies for the evaluation of polymeric food packaging components and determination of their structural and mechanical properties” (2016 DAN 1289) DS Minerva RD 27 abr 2026