RT Journal Article
T1 Duration versus intensity of exposure on the risk of lung cancer due to radon exposure in the general population
A1 Martín Gisbert, Lucía
A1 Ruano Raviña, Alberto
A1 García, Guadalupe
A1 Piñeiro Lamas, María
A1 García Talavera, Marta
A1 Teijeiro Teijeira, Ana
A1 Candal Pedreira, Cristina
K1 Lung cancer
K1 RadonCase-control study
K1 Radon-priority area
K1 Sex
AB Indoor radon causes lung cancer. The objective of this investigation is to describe lung cancer risk based both on duration and intensity of radon exposure, and to analyze if this effect could be different by sex. To do this, we used pooling information coming from very similar case-control studies on radon and lung cancer, all performed in a radon-priority area. We did a classical categorical analysis using logistic regressions to predict lung cancer risk for exposure duration, intensity of exposure and both variables combined, and we also employed generalized additive models to assess the risk of lung cancer. The results were obtained separately by sex. We included 3415 participants for whom radon measurements had been performed at their home, 1619 of whom were cases. We observed that the length and intensity of residential radon exposure might have a similar importance on lung cancer risk. For those living in dwellings with radon concentrations above 300 Bq/m3, lung cancer risk increases steadily and importantly with exposure duration, even with lengths of exposure above 40 years. We also observed that the risk of lung cancer might be higher in men compared to women. We encourage other researchers to reanalyze their data to confirm these results and also to test if the effect observed in women is replicated.
PB Elsevier
SN 0048-9697
YR 2025
FD 2025-06-15
LK https://hdl.handle.net/10347/43434
UL https://hdl.handle.net/10347/43434
LA eng
NO Martín-Gisbert, L., Ruano-Raviña, A., García, G., Piñeiro-Lamas, M., García-Talavera, M., Teijeiro, A., & Candal-Pedreira, C. (2025). Duration versus intensity of exposure on the risk of lung cancer due to radon exposure in the general population. Science of the Total Environment, 981, 179569. 10.1016/j.scitotenv.2025.179569
DS Minerva
RD 29 abr 2026