Single‐Molecule Approach to DNA Minor‐Groove Association Dynamics

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Molecularesgl
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Físicagl
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánicagl
dc.contributor.authorBordello Malde, Jorge
dc.contributor.authorSánchez López, Mateo Isidro
dc.contributor.authorVázquez Sentís, Marco Eugenio
dc.contributor.authorMascareñas Cid, José Luis
dc.contributor.authorAl-Soufi, Wajih
dc.contributor.authorNovo, Mercedes
dc.date.accessioned2019-03-27T12:35:54Z
dc.date.available2019-03-27T12:35:54Z
dc.date.issued2012
dc.descriptionThis is the peer reviewed version of the following article: Bordello, J. , Sánchez, M. I., Vázquez, M. E., Mascareñas, J. L., Al‐Soufi, W. and Novo, M. (2012), Single‐Molecule Approach to DNA Minor‐Groove Association Dynamics. Angew. Chem. Int. Ed., 51: 7541-7544, which has been published in final form at https://doi.org/10.1002/anie.201201099. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versionsgl
dc.description.abstractGetting in the groove: Fluorescence correlation spectroscopy reveals that the dynamics of the association process of the bisbenzamidine minor‐groove binder BBA‐OG (blue with green star, see scheme) to dsDNA is not controlled by diffusion, but by the insertion of the binder into the groove at the specific site (red), as shown by the rate constants for each step of the binding eventgl
dc.description.peerreviewedSIgl
dc.description.sponsorshipMinisterio de Ciencia e Innovación. Grant Numbers: CTQ2010‐21369, SAF2007‐61015, SAF2010‐20822‐C02, CTQ2009‐14431/BQU, CSD2007‐00006 Xunta de Galicia. Grant Numbers: INCITE09262304PR, INCITE09E2R209064ES, IN845B‐2010/094, INCITE09 209 084PR, GRC2010/12, PGIDIT08CSA‐047209PRgl
dc.identifier.citationBordello, J. , Sánchez, M. I., Vázquez, M. E., Mascareñas, J. L., Al‐Soufi, W. and Novo, M. (2012), Single‐Molecule Approach to DNA Minor‐Groove Association Dynamics. Angew. Chem. Int. Ed., 51: 7541-7544. doi:10.1002/anie.201201099gl
dc.identifier.doi10.1002/anie.201201099
dc.identifier.essn1521-3773
dc.identifier.issn1433-7851
dc.identifier.urihttp://hdl.handle.net/10347/18475
dc.language.isoenggl
dc.publisherWileygl
dc.relation.publisherversionhttps://doi.org/10.1002/anie.201201099gl
dc.rights© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versionsgl
dc.rights.accessRightsopen accessgl
dc.subjectBinding dynamicsgl
dc.subjectDNAgl
dc.subjectFluorescence correlation spectroscopygl
dc.subjectMinor-groove bindersgl
dc.subjectMolecular recognitiongl
dc.titleSingle‐Molecule Approach to DNA Minor‐Groove Association Dynamicsgl
dc.typejournal articlegl
dc.type.hasVersionAMgl
dspace.entity.typePublication
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relation.isAuthorOfPublication.latestForDiscovery34f1e1e8-411b-4b42-a25c-253481d3abef

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