Cross-sectional associations between Mediterranean diet and body composition in preschool children. CORAL study

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Abstract

Background: Overweight and obesity in children are rising globally, and the Mediterranean diet may help reduce obesity and related diseases. Objective: To assess the association between adherence to the Mediterranean diet and body composition in Spanish preschool children. Methods: This study included 1218 children aged 3-6 years from the CORALS cohort. Mediterranean diet adherence was evaluated using the validated MED4CHILD and COME-Kids F&B-FQ questionnaires. Body composition measurements included weight, height, waist circumference, BMI, Fat Mass (FM), Fat-Free Mass Index (FFMI), and Waist-to-Height ratio (WtHR). Multivariate regression and ANCOVA were used to examine associations, adjusting for factors like age, physical activity, and energy intake. We also performed a Cohen's d analysis to assess effect size. Results: Adherence to the Mediterranean diet was associated with more favourable body composition in children. Specifically, both the MED4CHILD score and the COME-Kids-derived score showed signif

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This is the peer reviewed version of the following article: [ Larruy-García A, Miguel-Berges ML, Torre IR-D, et al. Cross-sectional associations between Mediterranean diet and body composition in preschool children. CORAL study. Pediatric Obesity. 2025; 20(7):e70014], which has been published in final form at: https://doi.org/10.1111/ijpo.70014. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.

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Larruy-García, A., Miguel-Berges, M. L., Torre, I. R., Pastor-Villaescusa, B., Leis, R., Babio, N., Navas-Carretero, S., Corella, D., Pérez, A., Gil-Campos, M., Picáns-Leis, R., Garcia-Gavilán, J., Flores-Barrante, P., Martínez, J. A., Llorente-Cantarero, F. J., Vázquez-Cobela, R., Paz-Graniel, I., Ayala-Marín, A. M., Jurado-Castro, J. M., de la Torre-Aguilar, M. J., … CORAL Study group (2025). Cross-sectional associations between Mediterranean diet and body composition in preschool children. CORAL study. Pediatric obesity, 20(7), e70014. https://doi.org/10.1111/ijpo.70014

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LM, NB, MG-C, RL, SN-C and DC designed the study. AL-G did statistical analysis under the supervision of LM, PM-E and MLM-B, and AL-G wrote the manuscript.
All authors read and approved the final manuscript version. Funds for the establishment of the CORALS cohort in the first year of the study (2019) were provided by an agreement between the Danone Institute from Spain and the Centro de Investigación Biomédica en Red de la Fisiopatología de la Obesidad y Nutrición (CIBEROBN).
The authors would especially like to thank all the CORALS participants and their parents or caregivers as well as to the Health Centres and Primary Schools for their collaboration, to the CORALS personnel for their outstanding support, and to the staff of all associated primary care centres for their exceptional work.
Also, we thank to the PROMETEO Project 2021/21 from the Generalitat Valenciana (Conselleria de Universidades e Innovación).

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