Synthesis of new possible monoamine oxidase inhibitors

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URI: http://hdl.handle.net/10347/26873
ISBN: 3-906980-24-3
DOI: 10.3390/ecsoc-14-00474

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2010

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MDPI
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Abstract

We have generated different resveratrol-coumarin hybrids with the aim of evaluate their biological applications and their pharmacological properties, particularly the inhibitory activity of monoamine oxidase enzyme. According to that, a first series of 3-aryl-4-hydroxycoumarins has been synthesized starting from aryl boronic acids and phenyliodonium zwitterions precursors by a palladium-catalyzed coupling reaction

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The 14th International Electronic Conference on Synthetic Organic Chemistry session Natural Products Chemistry

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Coumarin| MAO| Suzuki reaction

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Proceedings of the 14th International Electronic Conference on Synthetic Organic Chemistry, 1–30 November 2010, MDPI: Basel, Switzerland, doi:10.3390/ecsoc-14-00474

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We are grateful to the Spanish Ministerio de Sanidad y Consumo (PS09/00501) and to Xunta da Galicia (CSA030203PR). Silvia Serra is grateful to Programma Master and Back PR_MAB‐ A2009‐613 Regione Sardegna

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© 2010 The author(s). Published by MDPI, Basel, Switzerland. Open Access

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Química Orgánica