Synthesis and Antimicrobial Activity of a Silver-Hydroxyapatite Nanocomposite
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Abstract
A silver-hydroxyapatite nanocomposite has been obtained by a colloidal chemical route and subsequent reduction process in H2/Ar atmosphere at C. This material has been characterized by TEM, XRD, and UV-Visible spectroscopy, showing the silver nanoparticles (65 nm) supported onto the HA particles (130 nm) surface without a high degree of agglomeration. The bactericidal effect against common Gram-positive and Gram-negative bacteria has been also investigated. The results indicated a high antimicrobial activity for Staphylococcus aureus, Pneumococcus and Escherichia coli, so this material can be a promising antimicrobial biomaterial for implant and reconstructive surgery applications.
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Díaz, M., Barba, F., Miranda, M., Guitián, F., Torrecillas, R., & Moya, J. S. (2009). Synthesis and antimicrobial activity of a silver-hydroxyapatite nanocomposite. Journal of Nanomaterials, 2009.
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https://doi.org/10.1155/2009/498505Sponsors
This work was supported by Bioker Research S.L. and by the Spanish Ministry of Education and Science under Project CENIT-INTELIMPLANT (ref.: 20071210). M. Díaz has been supported by Spanish Ministry of Education and Science and CSIC under I3P Program financed by European Social Fund
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Copyright © 2009 Marcos Díaz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited