Self-assembling alfa,gamma-cyclic peptides that generate cavities with tunable properties

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Molecularesgl
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánicagl
dc.contributor.authorRodríguez Vázquez, Nuria
dc.contributor.authorGarcía Fandiño, Rebeca
dc.contributor.authorAmorín López, Manuel
dc.contributor.authorGranja Guillán, Juan Ramón
dc.date.accessioned2018-05-28T12:49:50Z
dc.date.available2018-05-28T12:49:50Z
dc.date.issued2016-01-01
dc.description.abstractThe design and synthesis of β-sheet-based self-assembling cyclic peptides with tunable cavities is described. The incorporation of a γ-amino acid with a hydroxyl group at C2 allows the incorporation of different groups that modify the internal properties of the resulting dimeric ensemble. These dimers can entrap different guests depending on the properties of the group at C2. The guest defines the geometry of the resulting aggregategl
dc.description.peerreviewedSIgl
dc.description.sponsorshipThis work was supported by the Spanish Ministry of Economy and Competitivity (MINECO) and the ERDF (CTQ2010-15725 and CTQ2013-43264-R), and by the Xunta de Galicia and the ERDF (GPC2013-039, EM2012/117117 and EM2014/011011). N. R.-V. thanks MINECO for her FPU contract. We also thank the ORFEOCINCA network and MINECO (CTQ2014-51912-REDC) and the COST CM1306 European Actiongl
dc.identifier.citationRodríguez-Vázquez, N., García-Fandiño, R., Amorín, M., & Granja, J. (2016). Self-assembling α,γ-cyclic peptides that generate cavities with tunable properties. Chemical Science, 7(1), 183-187. http://dx.doi.org/10.1039/c5sc03187ggl
dc.identifier.doi10.1039/c5sc03187g
dc.identifier.essn2041-6539
dc.identifier.urihttp://hdl.handle.net/10347/16735
dc.language.isoenggl
dc.publisherRoyal Society of Chemistrygl
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2014-51912/ES/RED ORFEO-CINQA "CENTRO DE INNOVACION EN QUIMICA AVANZADA”
dc.relation.projectIDinfo:eu-repo/grantAgreement/MICINN/Plan Nacional de I+D+i 2008-2011/CTQ2010-1572/ES/NANOTUBOS PEPTIDICOS: SINTESIS Y APLICACIONES. HACIA UNA SINTESIS PRACTICA DE TAXANOS
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2013-43264-R/ES/NUEVAS TERAPIAS SUPRAMOLECULARES DIRIGIDAS A LAS MEMBRANAS LIPIDICAS Y BASADAS EN NANOESTRUCTURAS AUTOENSAMBLADAS
dc.relation.publisherversionhttp://dx.doi.org/10.1039/c5sc03187ggl
dc.rights(c) 2015 The Author(s). Published by Royal Society of Chemistry. This is an Open Access article distributed under the terms of the Creative Commons Attribution 3.0 Unported License (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citedgl
dc.rights.accessRightsopen accessgl
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.subjectSelf-assemblinggl
dc.subjectCyclic peptidesgl
dc.subjectSupramolecular chemistrygl
dc.subject.classificationMaterias::Investigación::23 Química::2306 Química orgánicagl
dc.titleSelf-assembling alfa,gamma-cyclic peptides that generate cavities with tunable propertiesgl
dc.typejournal articlegl
dc.type.hasVersionVoRgl
dspace.entity.typePublication
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relation.isAuthorOfPublication5c5f030f-17cc-4122-a603-7957ca9e0aab
relation.isAuthorOfPublicationfb6bbc55-1505-4e96-9863-825f7d16309c
relation.isAuthorOfPublication.latestForDiscovery7207f196-ba01-47c3-a5a7-dac268e007d3

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