Sonogashira versus Stephens-Castro Mediated Synthesis of o-Phenylethynylbenzoic Acids, Convenient Precursors of 3-Phenylisocoumarins

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URI: http://hdl.handle.net/10347/26853
ISBN: 3-906980-20-0
DOI: 10.3390/ecsoc-12-01201

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2008

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MDPI
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We describe herein two synthetic approaches to 3-phenyl-5-nitro-isocoumarines, both based on a nitro-facilitated cyclization of o-phenylethynylbenzoic acids obtained by Sonogashira or Stephens-Castro mediated coupling of o-yodobenzoic acids and phenylacetilenes

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The 12th International Electronic Conference on Synthetic Organic Chemistry session General Organic Synthesis

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Estévez, R.J.; Estévez, J.C.; Reboredo, F.J. Sonogashira versus Stephens-Castro Mediated Synthesis of o-Phenylethynylbenzoic Acids, Convenient Precursors of 3-Phenylisocoumarins, in Proceedings of the 12th International Electronic Conference on Synthetic Organic Chemistry, 1–30 November 2008, MDPI: Basel, Switzerland, doi:10.3390/ecsoc-12-01201

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© 2008 The author(s). Published by MDPI, Basel, Switzerland. Open Access

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