Nickel-promoted recognition of long DNA sites by designed peptide derivatives

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dc.contributor.affiliationUniversidade de Santiago de Compostela. Centro de Investigación en Química Biolóxica e Materiais Molecularesgl
dc.contributor.affiliationUniversidade de Santiago de Compostela. Departamento de Química Orgánicagl
dc.contributor.authorRodríguez Villar, Jéssica
dc.contributor.authorMosquera Mosquera, Jesús
dc.contributor.authorVázquez Sentís, Marco Eugenio
dc.contributor.authorMascareñas Cid, José Luis
dc.date.accessioned2016-12-14T08:36:50Z
dc.date.available2017-08-29T01:00:16Z
dc.date.issued2016-08-03
dc.descriptionNOTICE: This is the peer reviewed version of the following article: Jessica Rodríguez, Jesús Mosquera, M. Eugenio Vázquez*, José L. Mascareñas* (2016), Nickel-promoted Recognition of long DNA sites by designed Peptide Derivatives. ChemEurJ., 22 (38), 13474-13477 [doi:10.1002/chem.201602783]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for selfarchivinggl
dc.description.abstractWe describe the synthesis of designed peptidic modules that self-assemble in specific DNA sequences of 12 base pairs in the presence of NiII salts. The modules consist of modified fragments of transcription factors that have been appropriately engineered to include metal-chelating His and bipyridine ligandsgl
dc.description.peerreviewedSIgl
dc.description.sponsorshipWe are thankful for the support given by the Spanish grants SAF2013-41943-R, CTQ2015-70698-R, and CTQ2013-49317-EXP, the Xunta de Galicia GRC2013-041, the ERDF, and the European Research Council (Advanced Grant No. 340055). Support of COST Action CM1105, COST CM1306 and the orfeo-cinqa network are also kindly acknowledged. J.R. thanks the Xunta de Galicia for a PhD fellowshipgl
dc.identifier.citationJ. Rodríguez, J. Mosquera, M. E. Vázquez, J. L. Mascareñas, Chem. Eur. J. 2016, 22, 13474gl
dc.identifier.doi10.1002/chem.201602783
dc.identifier.issn1521-3765
dc.identifier.urihttp://hdl.handle.net/10347/15019
dc.language.isoenggl
dc.publisherWILEY-VCH Verlag GmbHgl
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/FP7/340055
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2013-49317/ES/EXPLORACION DE TERAPIAS ANTITUMORALES ALTERNATIVAS DIRIGIDAS A LAS MITOCONDRIAS
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SAF2013-41943-R/ES/HERRAMIENTAS SINTETICAS EN QUIMICA BIOLOGICA. NUEVAS ESTRATEGIAS MOLECULARES PARA EL TRATAMIENTO Y DIAGNOSTICO DE CANCERES
dc.relation.projectIDinfo:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2015-70698-R/ES/SISTEMAS SUPRAMOLECULARES PARA RECONOCIMIENTO BIOMOLECULAR: HELICATOS PEPTIDICOS Y RECEPTORES OLIGOMERICOS AUTOENSAMBLADOS
dc.relation.publisherversionhttp://dx.doi.org/10.1002/chem.201602783gl
dc.rights© WILEY-VCH Verlag GmbH & Co. KGaA, Weinheimgl
dc.rights.accessRightsopen accessgl
dc.subjectPeptidesgl
dc.subjectNickelgl
dc.subjectDNA recognitiongl
dc.subjectMetallosupramolecular chemistrygl
dc.subjectMinor groove bindergl
dc.subjectSelf-assemblygl
dc.subject.classificationMaterias::Investigación::23 Químicagl
dc.titleNickel-promoted recognition of long DNA sites by designed peptide derivativesgl
dc.typejournal articlegl
dc.type.hasVersionAMgl
dspace.entity.typePublication
relation.isAuthorOfPublication1b4c7a3c-215b-42bf-9ce2-c533031318dc
relation.isAuthorOfPublication34f1e1e8-411b-4b42-a25c-253481d3abef
relation.isAuthorOfPublication5ae222c9-f626-432b-aac5-da78c06ed64f
relation.isAuthorOfPublication.latestForDiscovery1b4c7a3c-215b-42bf-9ce2-c533031318dc

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