Programmed stereoselective assembly of DNA-binding helical metallopeptides

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ISSN: 1359-7345
E-ISSN: 1364-548X

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Royal Society of Chemistry
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A flexible and versatile synthetic approach for the construction of water-stable DNA-binding chiral peptide helicates based on the solid phase peptide synthesis (SPPS) methodology is reported

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Gamba, I., Rama, G., Ortega-Carrasco, E., Maréchal, J., Martínez-Costas, J., Eugenio Vázquez, M., & López, M. (2014). Programmed stereoselective assembly of DNA-binding helical metallopeptides. Chem. Commun., 50(76), 11097-11100. doi: 10.1039/c4cc03606a

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We are thankful for the support given by the Spanish grants SAF2010-20822-C02, CTQ2012-31341, CTQ2011-23336, CCTQ2010-16959 Consolider Ingenio 2010 CSD2007-00006, the Xunta de Galicia, GRC2010/12, GRC2013-041, PGIDIT08CSA-047209PR, and the Generalitat de Catalunya, 2009SGR68. Support of COST Action CM1105 is kindly acknowledged. G.R. thanks the INL for his PhD fellowship and E. O. the UAB for her PhD grant

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© The Royal Society of Chemistry 2014